Cell Therapy for Brain Injury

Front Matter....Pages i-xi
Introduction to Cell Therapy in Brain Injury....Pages 1-9
Cell-Based Therapeutics in Stroke: An Industry Perspective....Pages 11-20
Autologous Mesenchymal Stem Cell Therapy in Patients with Stroke....Pages 21-35
Treatment of Autologous Bone Marrow Mononuclear Cells for Acute and Subacute Stroke....Pages 37-46
Clinical Development of MultiStem® for Treatment of Injuries and Diseases of the Central Nervous System....Pages 47-63
Intra-arterial Approaches to Stem Cell Therapy for Ischemic Stroke....Pages 65-89
Neural Stem Cells in Stroke: Intracerebral Approaches....Pages 91-109
The CTX Human Neural Stem Cell Line and the PISCES Stroke Trial....Pages 111-128
Induced Pluripotent Stem Cells as a Cell-Based Therapeutic in Stroke....Pages 129-146
Induced Pluripotent Stem-Cell-Derived Neural Cell Types in Treatment of Stroke....Pages 147-172
Preconditioning and Cell-Based Therapeutics....Pages 173-186
Tracking of Administered Progenitor Cells in Brain Injury and Stroke by Magnetic Resonance Imaging....Pages 187-212
Biomaterials Application in Stem Cell Therapies for Stroke....Pages 213-245
A Stem-Cell-Derived Cell-Free Therapy for Stroke: Moving Conditioned Medium into Clinical Trial....Pages 247-265
Pathophysiology of Traumatic Brain Injury: Rationale and Role for Cellular Therapies....Pages 267-306
Stem Cell Therapy for Neonatal Hypoxic–Ischemic Brain Injury....Pages 307-320
Cell-Based Therapies in Neonatal Stroke....Pages 321-349
Issues in Clinical Trial Design in Stem Cell Trials After Stroke....Pages 351-364
Back Matter....Pages 365-369