Cell Signaling & Molecular Targets in Cancer

Front Matter....Pages i-xi
GRB2 Signaling as a Molecular Target for Cancer....Pages 1-22
Human Arylamine N -acetyltransferase 1: From Drug Metabolism to Drug Target....Pages 23-35
Targeting Argininosuccinate Synthetase in Cancer Therapy....Pages 37-51
Parathyroid Hormone–Related Peptide Signaling in Cancer....Pages 53-85
Signalling Molecules as Selective Targets for Therapeutic Strategies in Multiple Myeloma....Pages 87-108
Role of Bile Acids in Carcinogenesis of Gastrointestinal Tract....Pages 109-128
AIB1: A Transcriptional Coactivator Which Integrates Signaling Cross Talk in Cancer Cells....Pages 129-166
Rational Design of DNA Anticancer Agent That Targets Signal Transducer and Activator of Transcription 3 (Stat3) for Cancer Therapy....Pages 167-190
Estrogen Receptor Signaling in Lung Cancer....Pages 191-210
Microparticle Dissemination of Biological Activities: Implications for Cancer Biology....Pages 211-243
Protein Kinase D Signaling in Cancer....Pages 245-271
Cell Signaling and Cancer: Integrated, Fundamental Approach Involving Electron Transfer, Reactive Oxygen Species, and Antioxidants....Pages 273-297
Targeting Signal Transducer and Activator of Transcription (STAT) for Anticancer Therapy....Pages 299-321
Back Matter....Pages 323-328