Carotenoids in health and disease

Front cover......Page 1
Series Introduction......Page 7
Preface......Page 11
Contents......Page 13
Contributors......Page 17
Chapter 1. Basic Carotenoid Chemistry......Page 21
Chapter 2. Carotenoids and Radicals; Interactions with Other Nutrients......Page 51
Chapter 3. Noninvasive Assessment of Carotenoids in the Human Eye and Skin......Page 73
Chapter 4. Methodology for Assessment of Carotenoid Levels in Blood Plasma and Plasma Fractions......Page 105
Chapter 5. Carotenoid Antioxidant Activity......Page 125
Chapter 6. Evidence for Pro-Oxidant Effects of Carotenoids In Vitro and In Vivo: Implications in Health and Disease......Page 147
Chapter 7. Carotenoid Orientation: Role in Membrane Stabilization......Page 171
Chapter 8. Anticancer Activity of Carotenoids: From Human Studies to Cellular Processes and Gene Regulation......Page 185
Chapter 9. Induction of Cytochrome P450 Enzymes by Carotenoids......Page 217
Chapter 10. Impact of Food Processing on Content and Bioavailability of Carotenoids......Page 229
Chapter 11. Transport, Uptake, and Target Tissue Storage of Carotenoids......Page 249
Chapter 12. Bioequitanlence of Provitamin A Carotenoids......Page 299
Chapter 13. Bioconversion of Provitamin A Carotenoids......Page 315
Chapter 14. Carotenoid Oxidative/Degradative Products and Their Biological Activities......Page 333
Chapter 15. Conversion of Carotenoids to Vitamin A: New Insights on the Molecular Level......Page 357
Chapter 16. Enzymatic Versus Chemical Cleavage of Carotenoids: Supramolecular Enzyme Mimics for  -Carotene 15,15'-Monooxygenase......Page 377
Chapter 17. Relationship of Carotenoids to Cancer......Page 393
Chapter 18. Lycopene and Carcinogenesis......Page 429
Chapter 19. Carotenoids and Eye Disease: Epidemiological Evidence......Page 447
Chapter 20. Mechanistic Evidence for Eye Diseases and Carotenoids......Page 465
Chapter 21. Heart and Vascular Diseases......Page 493
Chapter 22. Carotenoids in Systemic Protection Against Sunburn......Page 511
Chapter 23. Carotenoids and Immune Responses......Page 523
Chapter 24. Therapeutic Uses ofCarotenoids in Skin Photosensitivity Diseases......Page 539
Chapter 25. Potential Adverse Effects of   -Carotene Supplementation in Cigarette Smokers and Heavier Drinkers......Page 551
Chapter 26. Carotenoids: Looking Forward......Page 567
Index......Page 573
Back cover......Page 589