Cardiac Valve Allografts 1962–1987: Current Concepts on the Use of Aortic and Pulmonary Allografts for Heart Valve Subsitutes

Front Matter....Pages I-XVI
Evolution of the biological concept in cardiac surgery: A Pilgrim’s Progress....Pages 1-11
Allogeneic valve procurement in cardiac transplantation....Pages 13-16
Antibiotic sterilisation in the preparation of homovital homograft valves: Is it necessary?....Pages 17-21
Procurement and viability of cardiac valve allografts....Pages 23-26
Cryobiology of tissues....Pages 27-34
Cryopreservation of aortic valve homografts....Pages 35-36
Factors affecting the viability of cryopreserved allograft heart valves....Pages 37-42
Endothelial and fibroblast viability assays for tissue allografts....Pages 43-48
Discussion....Pages 49-51
Contribution for discussion: Problems of homograft procurement....Pages 52-54
Contribution for discussion: Heart valve procurement in Berlin....Pages 55-57
Basic principles of transplantation immunology....Pages 59-64
Cryopreserved and fresh valved aortic homograft conduits in a chronic sheep model: Haemodynamic, angiographic and histological comparisons....Pages 65-68
Homograft valve calcification: Evidence for an immunological influence....Pages 69-74
Pathology of human explanted aortic valve homografts: A comparative morphological study with porcine aortic valve explants....Pages 75-76
Antigenicity and fate of cellular components of heart valve allografts....Pages 77-87
Immunohistopathology of cardiac valve allograft explants....Pages 89-94
Applications and limitations of histocompatibility in clinical cardiac valve allograft surgery....Pages 95-102
Discussion....Pages 103-106
The anatomy of the outflow tracts of the heart and of aortic and pulmonary allografts....Pages 107-111
Selection of allograft valve size....Pages 113-123
“Fresh” free-hand, non-viable allografts for aortic valve replacement: Operative techniques and 15-year results....Pages 125-140
Modified techniques for subcoronary insertion of allografts....Pages 141-147
Allograft aortic root replacement....Pages 149-155
Extended aortic root replacement in 12 patients with complex left ventricular outflow tract obstruction....Pages 157-165
Aortic root replacement with a cardiac allograft: The infected aortic root....Pages 167-171
Indications and surgical technique of aortic valve replacement with the autologous pulmonary valve....Pages 173-180
The morphology of tricuspid atresia, pulmonary atresia and truncus arteriosus....Pages 181-184
Population-based requirements for allograft surgery in children....Pages 185-187
The pulmonary allograft for right ventricular outflow tract reconstruction....Pages 189-193
Pulmonary valve allograft reconstruction of the right ventricular outflow tract....Pages 195-203
Technique of inlay allografts into the RVOT to prevent pulmonary insufficiency....Pages 205-213
Allografts in the treatment of absent pulmonary valve syndrome and complex tetralogy of Fallot....Pages 215-219
Technique of allograft repair of tetralogy of Fallot with pulmonary atresia....Pages 221-222
The use of aortic allografts in the primary repair of truncus arteriosus in early infancy and replacement of previous conduits....Pages 223-227
Allografts in the Rastelli procedure: Techniques....Pages 229-235
Allograft conduit for Fontan procedure....Pages 237-247
Late results of homograft function used for right ventricular outflow obstruction....Pages 249-259
Pulmonary autografts, viable and non-viable aortic homografts in the subcoronary position: A comparative study....Pages 261-264
Long-term results of antibiotic-treated aortic allografts in subcoronary position....Pages 265-271
Survival of aortic allografts containing living cells....Pages 273-280
Short-term results after allograft transplantation in the pulmonary position following previous repair of tetralogy of Fallot....Pages 281-290
Intermediate-term results of cryopreserved allograft and xenograft valved ventricle to pulmonary artery conduits....Pages 291-299
Functional evaluation of allografts by non-invasive techniques....Pages 301-309
Cryopreserved viable allograft aortic valves....Pages 311-321
Short-term follow-up of cryopreserved allograft valves and valved conduits from the CryoLife clinical registry....Pages 323-332
Discussion....Pages 333-343
Contribution for discussion: A mathematical model of aortic valve vibration....Pages 345-346
25 Years’ clinical experience of allograft surgery — A time for reflection....Pages 347-369
Panel Discussion....Pages 371-384
Summary....Pages 385-390
Closing Remarks....Pages 391-391
Back Matter....Pages 392-395