Cardiac Adaptations: Molecular Mechanisms

Front Matter....Pages i-xvii
Front Matter....Pages 1-1
Comparative Aspects of Cardiac Adaptation....Pages 3-18
Molecular Mechanisms of Cardiac Development....Pages 19-39
Prenatal Adaptations to Overload....Pages 41-57
Hypoxia and Mechanical Factors Drive Coronary Vascular Development....Pages 59-77
Cardiac Metabolic Adaptation During Postnatal Development....Pages 79-98
Ontogenetic Aspects of Cardiac Adaptation to Chronic Hypoxia....Pages 99-110
Heart and Arterial Aging....Pages 111-144
Front Matter....Pages 145-145
Differences in Concentric Cardiac Hypertrophy and Eccentric Hypertrophy....Pages 147-166
Cardiac Adaptation to Volume Overload....Pages 167-199
Functional Adaptation During the Development of Cardiac Hypertrophy and Heart Failure in Females....Pages 201-212
Impact of Gender and Exercise on Cardiac Adaptation to Pathological Situations: Sex Hormones, Exercise and Cardiac Adaptation....Pages 213-231
Cardiopulmonary Adaptation to High Altitude....Pages 233-249
Cardiac Hypertrophy in Hypertension....Pages 251-267
Exercise Training and Adverse Cardiac Remodeling and Dysfunction in Mice....Pages 269-287
The Athlete’s Heart....Pages 289-302
Front Matter....Pages 303-303
Role of β -Adrenoceptor/Adenylyl Cyclase System in Cardiac Hypertrophy....Pages 305-324
Role of Phospholipase C in the α 1 -Adrenoceptor Mediated Cardiac Hypertrophy....Pages 325-340
Cardiac Remodeling in the Hypertrophic Heart: Signal-Dependent Regulation of the Fibrotic Gene Program by CLP-1....Pages 341-359
Role of Sirtuins in Regulation of Cardiac Adaptation Associated with Hypertrophy....Pages 361-374
Adaptation of Cardiac and Skeletal Muscle Mitochondria to Endurance Training: Implications for Cardiac Protection....Pages 375-402
Front Matter....Pages 303-303
Adenosine as an Endogenous Adaptive Cardiac Antihypertrophic and Antiremodelling Factor....Pages 403-414
Myocardial Adaptation and Autophagy....Pages 415-432
Modulatory Role of VEGF in Angiogenesis for Cell Survival....Pages 433-445
The Role of CaM Kinase II in Cardiac Function in Health and Disease....Pages 447-461
Back Matter....Pages 463-465