Carcinogenicity of Inorganic Substances. Risks from Occupational Exposure

Content: 
Inside Front Cover, Page ii
Front Matter, Page iii
Copyright, Page iv
Preface, Pages v-vi
Organizers, Sponsors, Members of the Scientific and Editorial Board and Steering Organizing Committee, Page ix
Setting the Scene: The Scientific Context, Pages 1-5, J.H. DUFFUS
General Overview of the Scientific Presentations, Pages 6-18, M.H. DRAPER, J.H. DUFFUS
Bio-inorganic Chemistry and Cancer, Pages 19-38, R.J.P. WILLIAMS
Physico-chemical Properties of Inorganic Particles Controlling Biological Activity, Pages 39-57, R.P. NOLAN, A.M. LANGER
Mineralogical Factors and the Relationship of Fibres and Dusts in Humans to Disease, Pages 58-74, A. CHURG
In Vitro Studies of Genotoxicity and their Significance, Pages 75-85, M.-C. JAURAND
Sequence of Events in Lung Carcinogenesis, Pages 86-102, C.H. KENNEDY, J.F. LECHNER
The Significance of Toxicokinetics of Solid Particles in the Rat Lung, Pages 103-116, H. MUHLE
Mechanisms and Significance of Particle Overload, Pages 117-133, P.E. MORROW
Evaluating the Carcinogenicity of Crystalline Silica and Other Mineral Particles: Human, Animal, Cellular and Molecular Studies, Pages 134-145, U. SAFFIOTTI
Overview of Epidemiological Studies on the Carcinogenicity of Metals, Pages 146-159, A. BERNARD
Problems Encountered in Determining Metal Carcinogenesis through Epidemiological Studies, Pages 160-180, J.M. HARRINGTON
A Re-assessment of Respiratory Cancers at the Clydach Nickel Refinery: New Evidence of Causation, Pages 181-209, M.H. DRAPER
Introduction to Assessment of Carcinogenic Risk: International Activities, Regulations and the Industrial Situation, Page 210
The Role of the International Agency for Research on Cancer (IARC), Pages 211-212, P. BOFFETTA
IPCS Activities on Risk Assessment of Inorganic Compounds with Reference to Potency of Carcinogenicity, Pages 213-219, B.H. CHEN, E. SMITH
The Role of the US Occupational Safety and Health Administration, Pages 220-221, W. PERRY
The Role of the European Commission, Directorate General V, Pages 222-223, G. ARESINI
Chemical Substances – Classification and Labelling, Risk Assessment and Protection of Workers, Pages 224-228, J.M. COSTA-DAVID
Industry Views from a North American Perspective, Pages 229-234, I.M. ARNOLD
Industry Views from a European Perspective, Pages 235-242, L.G. MORGAN
Summary of the Panel and Plenary Discussion, Pages 243-245, M.H. DRAPER
Working Party 1 - Physico-chemical Characterisation of Exposures, Pages 246-249, A. LANGER, M.V. PARK
Working Party 2 - Interpretation of In Vitro and In Vivo Experimental Studies, Pages 250-253, U. SAFFIOTTI, K. SCHUMANN
Working Party 3 - Conduct and Interpretation of Epidemiological Studies, Pages 254-259, L.G. MORGAN, S. PORRU
Looking to the Future, Pages 260-264, J.H. DUFFUS
List of Seminar Participants, Pages 265-275
Subject Index, Pages 276-286