Carcinogen Risk Assessment

Front Matter....Pages i-ix
Front Matter....Pages 1-1
The Risk Analysis Process....Pages 3-17
Current Views of the Biology of Cancer....Pages 19-33
Front Matter....Pages 35-35
Use of Short-Term Test Data in Risk Analysis of Chemical Carcinogens....Pages 37-48
Use of Animal Bioassay Data in Carcinogen Risk Assessment....Pages 49-58
Front Matter....Pages 59-59
Assessing the Extent of Human Exposure to Organics....Pages 61-75
Partitioning Models....Pages 77-86
Pharmacokinetics....Pages 87-102
Front Matter....Pages 103-103
Biologically-Based Models to Predict Cancer Risk....Pages 105-113
Animal Extrapolation and the Challenge of Human Interindividual Variation....Pages 115-122
Biological Markers in Risk Assessment....Pages 123-138
Front Matter....Pages 139-139
Managing Environmental Risks....Pages 141-156
Acceptable Risk....Pages 157-170
Risk Perception....Pages 171-181
Risk Assessment and Comparisons....Pages 183-192
Risk Communication....Pages 193-207
Back Matter....Pages 209-210