Calcium Metabolism, Bone and Metabolic Bone Diseases

Front Matter....Pages I-XX
Front Matter....Pages 1-1
Morphological and Crystallographic Analysis of Bone Mineral....Pages 3-13
Quantitative Aspects of Calcium Metabolism and Homeostasis....Pages 14-24
A Time-Varying Model for Calcium Metabolism Including Diurnal Variations....Pages 25-30
Quality Control and Correlations of Clinical Methods for Studying Metabolic Bone Disease....Pages 31-31
Morphometric Microdensity Studies of Hard Tissue Sections, Utilising Optical Density Contour Maps and Associated Area Co-ordinated Computerised Data....Pages 33-38
On Calcium Metabolism during Immobilization....Pages 39-42
Limitations in Bone-Mass Measurements with 241 Am....Pages 43-46
Intestinal Absorption and Retention of Calcium Measured by Whole-Body Counting....Pages 47-51
Front Matter....Pages 53-53
Studies on the Metabolism, Mode of Action and Pharmacology of Vitamin D and Related Analogs....Pages 55-67
Vitamin D-Dependent Calcium Binding Protein of Rat Renal Cortex....Pages 68-73
The Effect of Disodium Ethane-1-Hydroxy-1, 1-Diphosphonate on the Metabolism of Vitamin D....Pages 74-75
The Effect of Estrogen on Calcium Binding Protein Activity in Odentogenic Epithelium of the Rat....Pages 76-79
Effect of Vitamin D on the Bone in Anticonvulsant Osteomalacia....Pages 81-86
The Effect of Vitamin D 3 on Lanthanum Absorption: Suggestive Evidence for a Shunt Path....Pages 87-90
The Effects of Cyclic AMP, Hormones and Ions on the Conversion of 25-Hydroxycholecalciferol (25-HCC) to 1,25-Dihydroxycholecalciferol (1,25-DHCC) in Isolated Chick Kidney Tubules....Pages 91-96
Extrarenal Metabolism of High Doses of 25-(OH)-D 3 : a New Active Metabolite....Pages 97-98
Front Matter....Pages 99-99
Fluoride and its Relation to Bone and Tooth....Pages 101-110
Absorption, Distribution in Body Fluids, and Bioavailability of Fluoride....Pages 111-121
Bone-Body Fluid Fluoride Balance....Pages 122-125
Possible Systemic Effects Following the Ingestion of Low Doses of Fluoride....Pages 126-130
Front Matter....Pages 99-99
Effects of Bone Fluoride on Bone Resorption and Metabolism....Pages 131-133
Urine Fluoride Levels Following Ingestion of Fluoridated Domestic Salt over Three Years....Pages 134-137
Fluoridation of Drinking Water and Bone Mineral Content, Analyzed by Monochromatic ( 125 I) Radiation Absorptiometry....Pages 138-142
Effects of Supply and Withdrawal of Fluoride on the Concentration of Fluoride and Glycosaminoglycans in Cortical Bone from Rabbits....Pages 143-145
Histological Bone Changes after Long-Term Treatment with Sodium Fluoride....Pages 146-150
Long-term Experience with Fluoride and Fluoride Combination Treatment of Osteoporosis....Pages 151-154
Front Matter....Pages 155-155
Collagen Structure and Calcification....Pages 157-163
Calcification of Collagenous Material in vitro as a Model System for Biological Calcification....Pages 164-169
Further Investigations on the Function of the Osteonic Lamellae According to Collagen and Crystallite Orientation....Pages 171-175
The Lability of Aldimine Crosslinks on Dissolution of Chicken Bone Collagen by Protein Denaturants....Pages 176-180
Comparison of Ca, P, and S Levels in Predentine and Tendon....Pages 181-183
The Role of Lysyl Residue in Collagen Structure with Calcification and Aging....Pages 184-188
Evidence for a Role of Lysozyme in Endochondral Calcification....Pages 189-189
The Formation of Bone Mineral....Pages 190-194
Front Matter....Pages 195-195
Biochemistry of Bone Diseases....Pages 197-210
Tetracycline Staining of Bone in Normal and Pathological States....Pages 211-217
Biochemical Determinations in Serum and Bone Homogenates from Patients with Femurhead Necroses....Pages 218-220
A Clinical and Biochemical Survey of Osteogenesis Imperfecta with Evidence for a Generalised Collagen Defect....Pages 221-225
Analysis of Tissue PO 2 and PCO 2 in Healing Bone....Pages 226-229
Front Matter....Pages 231-231
Effect of Various Therapies on Bone Loss in Women....Pages 233-242
Front Matter....Pages 231-231
Effect of Calcitonin in Paget’s Disease....Pages 243-247
Biochemical and Radiological Observations in Patients with Osteitis Deformans Treated with Synthetic Human Calcitonin....Pages 248-250
Influence of a Diphosphonate and 1,25-Dihydroxycholecalciferol on Calcium Metabolism....Pages 251-255
Effect of Various Doses of Disodium Ethane-1-Hydroxy-1,1-Diphosphonate (Sodium Etidronate, EHDP) on Suppression of the Biochemical and Histological Abnormalities in Paget’s Disease of Bone....Pages 256-262
Different Behavior of 45 Ca and 89 Sr in Chronic Uremia in the Rat....Pages 263-266
The Effect of 1,25-Dihydroxycholecalciferol in Patients with Vitamin D Resistant States (Chronic Renal Failure, Familial Hypophosphatemia, Gluten Sensitive Enteropathy and Hypoparathyroidism)....Pages 267-271
Treatment of Renal Osteodystrophy Using Vitamin D or High Dialysate Calcium Concentration....Pages 272-277
The Effects of Calcium Supplementation of the Diet on Bone Mass in Women....Pages 278-282
Front Matter....Pages 283-283
Chemical and Biologic Studies of Parathyroid Hormone, Proparathyroid Hormone, and Fragments of Parathyroid Hormone....Pages 285-294
Parathyroid Hormone: Structure and Immunoheterogeneity....Pages 295-315
Immuno-Reactive Parathyroid Hormone during EDTA Infusion in Chronic Renal Failure....Pages 316-320
Preliminary Studies on the Effect of Calcium on the Enzymatic Degradation of Human Calcitonin on the Dog....Pages 321-323
Factors Determining the Calcitonin Response in Man....Pages 324-325
Separation of the Hypocalcemic and Hypophosphatemic Effects of Calcitonin....Pages 326-327
Front Matter....Pages 329-329
Influences of Endogenous Parathyroid Hormone upon Development and Treatment (Calcium, Calcitonin, Sodium Fluoride) of Experimental Bone Atrophy....Pages 331-335
Quantitative Analysis of Bone Changes in Hypercalcitonism (C-Cell Carcinoma)....Pages 336-340
Intestinal Calcium Absorption 0–30 Years Post Gastrectomy; Study with a Double Isotope Radio Technique....Pages 341-342
The Morphology of the Intestinal Calcium Excretion by the Paneth Cell of Rat, Mouse and Man....Pages 343-348
Frictional Ablation — a Neglected Factor in the Mechanisms of Hard Tissue Destruction?....Pages 349-355
Tumoral Calcinosis with Hyperphosphatemia....Pages 356-361
Front Matter....Pages 329-329
Chronic Effects of Parathyroid Hormone Infused to Dogs at Near-Physiological Rates....Pages 362-366
The Calcium Orthophosphate Solubilities as Represented by a Model in Three Dimensions....Pages 367-372
Back Matter....Pages 373-384