Brain Phosphoproteins: Characterization and Function, Proceedings of a Workshop at the State University of Utrecht

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Page iii

Copyright page
Page iv

Preface
Page v
Willem Hendrik Gispen, Aryeh Routtenberg

Participants
Pages vi-ix

Aspects of Protein Phosphorylation in the Nervous System with Particular Reference to Synaptic Transmission Original Research Article
Pages 1-25
Richard Rodnight

Identification and Topography of Synaptic Phosphoproteins Original Research Article
Pages 27-48
Henry R. Mahler, Leonard P. Kleine, Nancy Ratner, Roger G. Sorensen

Phosphoproteins in Postsynaptic Densities Original Research Article
Pages 49-76
Rochelle S. Cohen, Richard K. Carlin, Dennis J. Grab, Philip Siekevitz

Immunocytochemical Localization of Identified Proteins in Brain by Monoclonal Antibodies Original Research Article
Pages 77-86
Richard Hawkes, Meelian Ng, Evelyn Niday, Andrew Matus

Specific Inhibition of the Phosphorylation of Protein I, a Synaptic Protein, by Affinity-Purified Anti-Protein I Antibody Original Research Article
Pages 87-103
Tetsufumi Ueda, Shigetaka Naito

Cyclic GMP-Dependent Protein Phosphorylation in Mammalian Cerebellum Original Research Article
Pages 105-123
Doris J. Schlichter

Calcium Ion Stimulated Protein Kinases in Myelin Original Research Article
Pages 125-144
Elena H. Petrali, Prakash V. Sulakhe

The Regulation of Enzyme Activity by Reversible Phosphorylation Original Research Article
Pages 145-161
D. Grahame Hardie, Paul S. Guy

Substrates of Nuclear Protein Kinases in Rat C6 Glial Cell Cultures Original Research Article
Pages 163-178
Richard A. Jungmann, Janie J. Harrison, Deborah Milkowski, Seung-Ki Lee, John S. Schweppe, Michael F. Miles

Activation of Multiple S6 Phosphorylation and its Possible Role in the Alteration of mRNA Expression Original Research Article
Pages 179-194
G. Thomas

Ribosomal Protein Phosphorylation and Protein Synthesis in the Brain Original Research Article
Pages 195-211
Sidney Roberts

Phosphorylation in Relation to the Modulation of Brain Protein Synthesis by ACTH-Like Neuropeptides Original Research Article
Pages 213-235
P. Schotman, H. Frankena, L.H. Schrama, P.M. Edwardss

Role of Calmodulin in Brain Function Original Research Article
Pages 237-253
Wai Yiu Cheung

Ca2+-Calmodulin Tubulin Kinase System and its Role in Mediating the Ca2+ Signal in Brain Original Research Article
Pages 255-286
Robert J. Delorenzo, Basilio Gonzalez, James Goldenring, Allen Bowling, Ronald Jacobson

Membrane Phospholipid Turnover, Receptor Function and Protein Phosphorylation Original Research Article
Pages 287-301
Yoshimi Takai, Ryoji Minakuchi, Ushio Kikkawa, Kimihiko Sano, Kozo Kaibuchi, Binzu Yu, Tsukasa Matsubara, Yasutomi Nishizuka

B-50 Protein Kinase and Kinase C in Rat Brain Original Research Article
Pages 303-315
V.J. Aloyo, H. Zwiers, W.H. Gispen

Evidence that High Frequency Stimulation Influences the Phosphorylation of Pyruvate Dehydrogenase and that the Activity of this Enzyme is Linked to Mitochondrial Calcium Sequestration Original Research Article
Pages 317-337
M. Browning, M. Baudry, G. Lynch

Changes in Membrane Phosphorylation Correlated with Long-Lasting Potentiation in Rat Hippocampal Slices Original Research Article
Pages 339-347
F.H. Lopes Da Silva, P.R. Bär, A.M. Tielen, W.H. Gispen

Identification and Back-Titration of Brain Pyruvate Dehydrogenase: Functional Significance for Behavior Original Research Article
Pages 349-374
Aryeh Routtenberg

Protein Phosphorylation in the Regulation and Adaptation of Receptor Function Original Research Article
Pages 375-396
Yigal H. Ehrlich, Scott R. Whittemore, Mark K. Garfield, Stephen G. Graber, Robert H. Lenox

Modulation of Adenylate Cyclase by Protein Phosphorylation: Effects of ACTH Original Research Article
Pages 397-404
V.M. Wiegant, J.M.H.M. Reul, W.H. Gispen

ACTH and Synaptic Membrane Phosphorylation in Rat Brain Original Research Article
Pages 405-417
H. Zwiers, J. Jolles, V.J. Aloyo, A.B. Oestreicher, W.H. Gispen

The Modulation of Protein Phosphorylation and Receptor Binding in Synaptic Membranes by Changes in Lipid Fluidity: Implications for Ageing Original Research Article
Pages 419-434
Moshe Hershkowitz, David Heron, David Csamuel, Meir Shinitzky

Proposed Role of Phosphoproteins in Visual Function Original Research Article
Pages 435-445
Debora B. Farber

Author Index
Page 447

Subject Index
Pages 449-452