Brain Injury and Pediatric Cardiac Surgery

PART I DEVELOPMENT OF THE CENTRAL NERVOUS SYSTEM: Brain Development and its Relationship to PAtterns of Injury 
  Maturation of Brain ATP Metabolism 
  EEG Maturation with Special Reference to Epiletogenic Effects of Hypoxia 
  Programmed Cell Death 
  The Biology of Cell Death in the Nematode Caenorhabditid elegans and Implications for the Understanding and Treatment of Human Brain Injury after Cardiac Surgery. PART II ASSESSMENT OF CNS FUNCTION: The Neurological Examination 
  Cognitive and Psychomotor Developmental Assessment 
  EEG Methods with PArticular Reference to Neonatal Seizures 
  Transcranial Doppler Technology: The Noninvasive Monitoring of Cerebral Perfusion During Cardiopulmonary Bypass 
  PET and SPECT in the Assessment of Cerebral Function 
  Brain Monitoring Using Optical Imaging and Optical Spectroscopy 
  Assessment of CNS Function: Cerebral Blood Flow and Metabolism 
  Cerebral Evaluation with Nuclear Magnetic Resonance Spectroscopy. PART III MECHANISMS OF NEUROLOGICAL INJURY: Mechanisms of Perinatal Ischemic Brain Damage 
  Endothelial and White Cell Activation in Bypass and Reperfusion Injury: Brain Injury 
  Excitotoxicity and Nitric Oxide. 
  PART IV CLINICAL AND LABORATORY STUDIES OF CARDIOPULMONARY BYPASS, HYPOTHERMIA AND CIRCULATORY ARREST: A Newborn Canine Model of Hypothermic Circulatory Arrest 
  Effects on CPB, Hypothermia and Circulatory Arrests on Cerebral Blood Flow and Metabolism 
  Assessment by NMRS of the Effects of Cardiopulmonary Bypass, Hypothermia and Circulatory Arrest 
  pH MANAGEMENT During Hypothermic Cardiopulmonary Bypass with Circulatory Arrest. PART V A PROSPECTIVE CLINICAL STUDY OF CIRCULATORY ARREST AT CHILDREN`S HOSPITAL, BOSTON: Methods and Procedures 
  EEG Findings 
  Neurologic and MRI Findings