Brain Acetylcholine and Neuropsychiatric Disease

Front Matter....Pages i-xvi
Front Matter....Pages 1-1
Psychological Effects of Cholinomimetic Agents....Pages 3-14
Pharmacological Investigations of Cholinergic Mechanisms in Schizophrenia and Manic Psychosis....Pages 15-32
Affective Changes with Deanol....Pages 33-44
Lithium and Acetylcholine Interactions....Pages 45-51
Cerebrospinal Fluid Acetylcholinesterase in Psychosis and Movement Disorders....Pages 53-61
Brain Cholinergic Enzymes in Schizophrenia....Pages 63-74
Red Cell Choline and Affective Disease....Pages 75-83
Front Matter....Pages 85-85
Treatment of Huntington’s Disease and Tardive Dyskinesia with Choline Chloride....Pages 87-97
Choline Administration to Patients with Huntington’s Disease or Tardive Dyskinesia....Pages 99-120
Deanol Trials in Tardive Dyskinesia....Pages 121-142
Oral Physostigmine and Inherited Ataxias....Pages 143-154
Alterations in Muscarinic Cholinergic Receptor Binding in Huntington’s Disease....Pages 155-172
Front Matter....Pages 173-173
Cholinergic Excitability and Memory: Animal Studies and their Clinical Implications....Pages 175-204
Brain Acetylcholine and Disorders of Memory....Pages 205-213
Carbohydrates and Acetylcholine Synthesis: Implications for Cognitive Disorders....Pages 215-236
Cognitive Effects of Physostigmine and Choline Chloride in Normal Subjects....Pages 237-251
The Treatment of Memory Deficits in the Aged with Choline Chloride....Pages 253-262
Front Matter....Pages 263-263
Brain Acetylcholine and Animal Electrophysiology....Pages 265-310
Acetylcholine: Possible Involvement in Sleep and Analgesia....Pages 311-343
Electrophysiological Effects of Physostigminein Humans....Pages 345-360
Front Matter....Pages 263-263
Electrophysiological Effects of Choline Chloride in Elderly Subjects....Pages 361-370
Front Matter....Pages 371-371
The Role of Cholinergic and Dopaminergic Interactions in Diseases of the Central Nervous System....Pages 373-393
Interactions Between Acetylcholine and Dopamine in the Basal Ganglia....Pages 395-424
Evidence for the Existence of Two Striatal Dopamine Receptors....Pages 425-434
Physostigmine Related Changes in Cerebrospinal Fluid Neurotransmitter Metabolites in Man....Pages 435-443
Acetylcholine and Anterior Pituitary Hormone Secretion....Pages 445-458
Front Matter....Pages 459-459
Dietary Control of Central Cholinergic Activity....Pages 461-481
The Neurochemical Basis of Acetylcholine Precursor Loading as a Therapeutic Strategy....Pages 483-513
Choline Availability — Choline High Affinity Transport and the Regulation of Acetylcholine Synthesis....Pages 515-531
Pharmacokinetic Studies with Choline Chloride: A Preliminary Report....Pages 533-539
Choline Chloride: Effect on Hyperdopaminergic States in Animals....Pages 541-547
Back Matter....Pages 549-597