Biological Functions of Proteinases

Front Matter....Pages I-IX
Conformational Flexibility and Its Functional Significance in Some Protein Molecules....Pages 1-16
Intracellular Protein Turnover....Pages 17-34
Studies of the Pathway for Protein Degradation in Escherichia coli and Mammalian Cells....Pages 35-48
Lysosomes and Intracellular Proteolysis....Pages 49-54
Genetic and Biochemical Analysis of Intracellular Proteolysis in Yeast....Pages 55-72
Endogenous Inhibitors of Tissue Proteinases....Pages 73-86
Activity of a Rat Uterus Proteinase Inhibitor During Pregnancy and Involution Its Possible Importance in Control of Proteolysis in the Myometrium....Pages 87-93
Alkaline Proteinases in Skeletal Muscle....Pages 94-101
Determinants in Protein Topology....Pages 102-108
Import of Proteins into Mitochondria....Pages 109-119
Localization and Some Properties of a Proteinase and a Carboxypeptidase from Rat Liver....Pages 120-127
Processing of Bacteriophage Proteins....Pages 128-138
Proteolysis, a Determinant for Virus Pathogenicity....Pages 139-149
The Processing of Plasma Proteins in the Liver....Pages 150-164
Protease Action in Carcinogenesis....Pages 165-170
Plasminogen Activator from Cultured Cells and from Blood Plasma....Pages 171-185
Role of Proteinases from Leukocytes in Inflammation....Pages 186-195
Role of Granulocyte Elastase in Rheumatoid Arthritis: Effect on Mechanical Behaviour of Cartilage and Identification at the Cartilage/Pannus Junction....Pages 196-206
Regulation of Proteinase Acitvity....Pages 207-222
The Complement System....Pages 223-232
Substrate Modulation as a Control Mechanism of Plasma Multienzyme Systems....Pages 233-237
Blood Coagulation....Pages 238-242
The Kallikrein-Kinin System: A Functional Role of Plasma Kallikrein and Kininogen in Blood Coagulation....Pages 243-259
Hydrolysis of Peptide Bonds and Control of Blood Pressure....Pages 260-268
Characterization of the Active Site of Angiotensin Converting Enzyme....Pages 269-275
Proteolysis and Fertilization....Pages 276-277
Back Matter....Pages 279-286