Bioinformatics Research and Applications: 10th International Symposium, ISBRA 2014, Zhangjiajie, China, June 28-30, 2014. Proceedings

Front Matter....Pages -
Predicting Disease Risks Using Feature Selection Based on Random Forest and Support Vector Machine....Pages 1-11
Phylogenetic Bias in the Likelihood Method Caused by Missing Data Coupled with Among-Site Rate Variation: An Analytical Approach....Pages 12-23
An Eigendecomposition Method for Protein Structure Alignment....Pages 24-37
Functional Interplay between Hemagglutinin and Neuraminidase of Pandemic 2009 H1N1 from the Perspective of Virus Evolution....Pages 38-49
Predicting Protein Submitochondrial Locations Using a K-Nearest Neighbors Method Based on the Bit-Score Weighted Euclidean Distance....Pages 50-58
Algorithms Implemented for Cancer Gene Searching and Classifications....Pages 59-70
Dysregulated microRNA Profile in HeLa Cell Lines Induced by Lupeol....Pages 71-80
 A Simulation for Proportional Biological Operational Mu-Circuit ....Pages 81-91
Computational Prediction of Human Saliva-Secreted Proteins....Pages 92-101
A Parallel Scheme for Three-Dimensional Reconstruction in Large-Field Electron Tomography....Pages 102-113
An Improved Correlation Method Based on Rotation Invariant Feature for Automatic Particle Selection....Pages 114-125
An Effective Algorithm for Peptide de novo Sequencing from Mixture MS/MS Spectra....Pages 126-137
Identifying Spurious Interactions in the Protein-Protein Interaction Networks Using Local Similarity Preserving Embedding....Pages 138-148
Multiple RNA Interaction with Sub-optimal Solutions....Pages 149-162
Application of Consensus String Matching in the Diagnosis of Allelic Heterogeneity....Pages 163-175
Continuous Time Bayesian Networks for Gene Network Reconstruction: A Comparative Study on Time Course Data....Pages 176-187
Drug Target Identification Based on Structural Output Controllability of Complex Networks....Pages 188-199
NovoGMET: De Novo Peptide Sequencing Using Graphs with Multiple Edge Types (GMET) for ETD/ECD Spectra....Pages 200-211
Duplication Cost Diameters....Pages 212-223
Computational Identification of De-Centric Genetic Regulatory Relationships from Functional Genomic Data....Pages 224-235
Classification of Mutations by Functional Impact Type: Gain of Function, Loss of Function, and Switch of Function....Pages 236-242
Network Analysis of Human Disease Comorbidity Patterns Based on Large-Scale Data Mining....Pages 243-254
Identification of Essential Proteins by Using Complexes and Interaction Network....Pages 255-265
 GenoScan: Genomic Scanner for Putative miRNA Precursors ....Pages 266-277
Searching SNP Combinations Related to Evolutionary Information of Human Populations on HapMap Data....Pages 278-288
2D Pharmacophore Query Generation....Pages 289-300
Structure-Based Analysis of Protein Binding Pockets Using Von Neumann Entropy....Pages 301-309
A New Mathematical Model for Inbreeding Depression in Large Populations....Pages 310-321
dSpliceType: A Multivariate Model for Detecting Various Types of Differential Splicing Events Using RNA-Seq....Pages 322-333
Conformational Transitions and Principal Geodesic Analysis on the Positive Semidefinite Matrix Manifold....Pages 334-345
Joint Analysis of Functional and Phylogenetic Composition for Human Microbiome Data....Pages 346-356
 schematikon : Detailed Sequence-Structure Relationships from Mining a Non-redundant Protein Structure Database....Pages 357-366
Back Matter....Pages -