Biochemical Pharmacology as an Approach to Gastrointestinal Disorders: Basic Science to Clinical Perspectives (1996)

Front Matter....Pages i-x
Introduction: Advances in the Biochemical Pharmacology of Gastrointestinal (GI) Functions as an Approach to Understanding GI Disorders....Pages 1-4
Front Matter....Pages 5-5
Possible Compensation in Epidermal Growth Factor Production by Saliva in Rat....Pages 7-23
Regulatory Mechanism of Acid Secretion in Rat Stomach After Damage — Role of Nitric Oxide, Histamine and Sensory Neurons....Pages 25-37
Secretory Pathways in Histamine-Containing Enterochromaffin-Like Cells of Rat Stomach....Pages 39-55
Nitric Oxide as a Modulator of Fluid Absorption in Rat Jejunum in Vivo....Pages 57-64
Mechanism of Cholera....Pages 65-72
Critical Evaluation of Acinar, Ductal, Vascular and Intestinal Intraluminal Factors Influencing Pancreatic Cytoprotection....Pages 73-82
Peptide Receptor Antagonists and Monoclonal Antibodies Raised Against Peptides: Tools to Study Physiological Regulation of Pancreatic Function....Pages 83-94
Mechanisms and Regulation of C1 - Secretion in the Large Intestine: Studies with the Rat Distal Colon....Pages 95-102
Front Matter....Pages 103-103
Prostaglandin E 2 : Actions on the Circular and Longitudinal Contractions of the Canine Colon....Pages 105-114
Gastric Motor Effects of Endothelins in the Lower Brainstem of the Rat....Pages 115-123
Effects of Erythromycin on the Propulsive Motility of Upper Gastrointestinal Tract in Rats....Pages 125-130
Bicuculline Blocks the Inhibitory Effects of Substance P but not Vasoactive Intestinal Polypeptide on Gastric Motor Function in the Nucleus Raphe Obscurus of the Rat....Pages 131-139
Pathological Basis and Clinical Aspects of Oesophageal Motor Disorders....Pages 141-167
Front Matter....Pages 169-169
Distribution of Muscarinic Receptor mRNAs in the Stomachs of Normal or Immobilized Rats....Pages 171-185
Changes of Sensory Neuropeptides in Experimental Gastrointestinal Diseases....Pages 187-195
Front Matter....Pages 197-197
Biochemical Energy Backgrounds and Their Regulation in the Gastric Corpus Mucosa in Patients with Different Gastric Secretory Responses....Pages 199-223
Oxidative Stress and its Prevention in Toxic Liver Lesions. An Overview....Pages 225-237
The Effect of Drugs on Liver Function and Biliary Secretion....Pages 239-247
Alteration of Microvascular Regeneration and Permeability during Acetic Acid-Induced Gastric Ulcer Healing: Effect of Basic Fibroblast Growth Factor....Pages 249-259
Front Matter....Pages 197-197
Modulation of Gastric Wound Repair by Hepatocyte Growth Factor and Basic Fibroblast Growth Factor....Pages 261-268
The Effect of Resiniferatoxin on Experimental Gastric Ulcer in Rats....Pages 269-285
Aids Treatment and the Heat Shock Protein Level in the Gastrointestinal Tract....Pages 287-295
Elisa and Western Blot Studies with Basic Fibroblast Growth Factor (bFGF) and Platelet-Derived Growth Factor (PDGF) in Experimental Duodenal Ulceration and Healing....Pages 297-301
Biological Oxidants as Intestinal Secretagogues....Pages 303-311
A New Uniform Biochemical Explanation for the Development and Location of ‘Genuine’ Gastric, Duodenal and Jejunal Ulcers in Patients....Pages 313-334
Front Matter....Pages 335-335
Current Problems and Results of Tumour Immunology: Diagnostic and Therapeutic Relevance of Tumour-Associated Antigens....Pages 337-346
Front Matter....Pages 347-347
Does Omeprazole-Induced Hypergastrinaemia Contribute to the Enhanced Healing of Acetic Acid-Induced Gastric Ulcers in Rats?....Pages 349-359
Modification of Pathobiological Events by Potential Hepatopharmacological Agents....Pages 361-371
Organoprotection and Cytoprotection of Histamine Differ in Rats....Pages 373-385
Comparative Viability Studies on Isolated Gastric Mucosal Mixed Cells and Hepatoma and Myeloma Cell Lines with Ethanol, Indomethacin and Their Combination....Pages 387-394
Back Matter....Pages 395-396