Biochemical Mechanisms in Heart Function

Front Matter....Pages i-2
Front Matter....Pages 3-3
Control of cardiac performance by Ca-turnover....Pages 5-12
Deformation of the Bowditch staircase in Ca 2+ -overioaded mammalian cardiac tissue — a calcium phenomenon?....Pages 13-25
Cooperative interaction between Ca 2+ binding sites in the hydrophilic loop of the Na + -Ca 2+ exchanger....Pages 27-32
E-1020, a water soluble imidazopyridine, has direct effects on Ca 2+ -dependent force and ATP hydrolysis of canine and bovine cardiac myofilaments....Pages 33-39
Primary cultures of cardiac muscle cells as models for investigation of protein glycosylation....Pages 41-46
Influence of glycosylation inhibitors on dihydropyridine binding to cardiac cells....Pages 47-52
Comparative study of cardiac electrophysiological effects of atrial natriuretic peptide....Pages 53-59
Effect of TaiCatoxin (TCX) on the electrophysiological, mechanical and biochemical characteristics of spontaneously beating ventricular cardiomyocytes....Pages 61-66
Pharmacological characteristics of endothelin receptors in the rabbit ventricular myocardium: The nonselective endothelin receptor antagonist PD 145065 antagonizes the positive inotropic effect of endothelin-3 but not of endothelin-1....Pages 67-74
Involvement of nitric oxide synthase and protein kinase C activation on chagasic antibodies action upon cardiac contractility....Pages 75-82
Kinetics of myocardial phospholipase D....Pages 83-87
Is cysteine residue important in FITC-sensitive ATP-binding site of P-type ATPases? A commentary to the state of the art....Pages 89-93
Reinstatement of the ATP high energy paradigm....Pages 95-99
Regulation of and intervention into the oxidative pentose phosphate pathway and adenine nucleotide metabolism in the heart....Pages 101-109
The endogenous digitalis-like factor....Pages 111-115
Functional antagonism by a monoclonal antibody to digoxin in a test system of cultured rat heart myocytes....Pages 117-120
Front Matter....Pages 121-121
Biphasic changes in relaxation following reperfusion after myocardial ischemia....Pages 123-128
Signal transduction in myocardial ischaemia and reperfusion....Pages 129-136
Reversible and irreversible damage in reoxygenated ‘ischemic’ ventricular myocytes in culture....Pages 137-141
Effects of hypoxia, simulated ischemia and reoxygenation on the contractile function of human atrial trabeculae....Pages 143-151
Front Matter....Pages 121-121
The guanine nucleotide-binding regulatory proteins (G proteins) in myocardium with ischemia....Pages 153-158
Role of reactive oxygen species in cardiovascular aging....Pages 159-166
Uncoupling of mitochondrial oxidative phosphorylation alters lipid peroxidation-derived free radical production but not recovery of postischemic rat hearts and post-hypoxic endothelial cells....Pages 167-177
Relationship between mechanical dysfunction and depression of sarcolemmal Ca 2+ -pump activity in hearts perfused with oxygen free radicals....Pages 179-185
Relation between energy metabolism, glycolysis, noradrenaline release and duration of ischemia....Pages 187-194
On the regulation of cellular energetics in health and disease....Pages 195-208
Salvage of jeopardized myocardium by ischemic preconditioning: Is the quest over?....Pages 209-215
Cytoprotective mechanisms in cultured cardiomyocytes....Pages 217-224
Delayed cardioprotection is associated with the sub-cellular relocalisation of ventricular protein kinase Cε, but not p42/44MAPK....Pages 225-230
HSP25 in isolated perfused rat hearts: Localization and response to hyperthermia....Pages 231-239
Molecular cloning, sequencing and expression analysis of a fatty acid transport gene in rat heart induced by ischemic preconditioning and oxidative stress....Pages 241-247
Protaglandins and the antiarrhythmic effect of preconditioning in the isolated rat heart....Pages 249-255
Prevention by 7-oxo-prostacyclin of the calcium paradox in rat heart: Role of the sarcolemmal (Na,K)-ATPase....Pages 257-263
Donors of nitric oxide mimic effects of ischaemic preconditioning on reperfusion induced arrhythmias in isolated rat heart....Pages 265-271
Crucial role of intracellular effectors on glycogenolysis in the isolated rat heart: Potential consequences on the myocardial tolerance to ischemia....Pages 273-282
Probucol treatment reverses antioxidant and functional deficit in diabetic cardiomyopathy....Pages 283-288
Glycogen phosphorylase isoenzyme BB in diagnosis of myocardial ischaemic injury and infarction....Pages 289-295
Unaltered ryanodine receptor protein levels in ischemic cardiomyopathy....Pages 297-302
Myocardial infarction and nitric oxide....Pages 303-306
Estrogen effects in the heart....Pages 307-313
Front Matter....Pages 121-121
Xenoreactive natural antibodies and induced antibodies — their effects on beating cardiomyocytes as a model of a xenograft....Pages 315-323
Back Matter....Pages 325-329