Bioactive Spin Labels

Front Matter....Pages I-X
Spin-Labeled Medicines: Enzymes, Biomembranes and Possible Pharmaceuticals. An Overview....Pages 1-21
Nitroxyl Radicals and Non-Radical Reactions of Free Radicals....Pages 23-82
Triacetonamine in the Chemistry of Nitroxyl Radicals....Pages 83-118
Catalysis of Redox Processes by Nitroxyl Radicals....Pages 119-140
Biomembrane Reactions of Nitroxyl Radicals....Pages 141-179
Relaxation Processes Involving Nitroxyl Radicals in Molecular Biology....Pages 181-200
Investigations on Spin Exchange in Nitroxyls by the Method of Continuous Saturation of EPR Spectra....Pages 201-214
Spin Exchange Components in Nitroxyl Biradicals EPR Spectra....Pages 215-225
Investigation of Spin Labels and Probes by Millimeter Band EPR....Pages 227-278
Analysis of Spin Label Slow Motions Based on Simulating 2-MM Band EPR Spectra....Pages 279-296
Synthesis and Properties of Spin-Labeled Phospholipids....Pages 297-315
Spin-Labeled Phospholipids for Protein—Lipid Interactions....Pages 317-336
Spin-Labeled Organophosphorus Compounds....Pages 337-353
Spin-Labeled Close Analogs of Sugars and Nucleosides....Pages 355-387
Spin-Labeling Study of the Structure and Function of Leucine Aminopeptidase....Pages 389-403
Photoaffinity Spin Labeling....Pages 405-427
The Toxicity of Aminoxyl Radicals....Pages 429-438
Nitroxyl Radicals for Cancer Chemotherapy....Pages 439-460
Spin Labeling Study of Platelet Plasma Membrane and Nitroxyl Aggregation Inhibitors....Pages 461-489
Anti-Ischemic Effect of 1-Hydroxy Derivatives of Nitroxyl Bioantioxidants....Pages 491-507
Spin Probes for the Study of Intact and Cancer Cell Membranes....Pages 509-526
Pharmacokinetics of Nitroxyl Radicals....Pages 527-548
Computer-Assisted Evaluation of Nitroxyl Radical Effect on Biological Activity....Pages 549-571
Aminoxyl Radicals as MRI Contrast Agents....Pages 573-583
Aminoxyl Spin Labels in Clinical Analysis....Pages 585-610
Applications of Spin-Label Techniques at High Pressures....Pages 611-629
Back Matter....Pages 631-636