Balanced Alpha/Beta Blockade of Adrenoceptors / Balancierte Blockade von Alpha- und Beta-Adrenozeptoren: A rational therapeutic concept in the treatment of hypertension and coronary heart disease / Ein rationales Konzept zur Behandlung der Hypertonie und der koronaren Herzerkrankungen

Front Matter....Pages I-VIII
Front Matter....Pages 1-1
Das ideale Antihypertensivum — Wunschdenken und Wirklichkeit....Pages 3-15
The Pharmacodynamics of Alpha and Beta Blockade....Pages 17-24
Zur Chronopharmakologie von Adrenozeptorenblockem....Pages 25-32
The Response of Plasma Catecholamines to Receptor Antagonists....Pages 33-41
Front Matter....Pages 43-43
The Clinical Profiles of Long Term Labetalol Therapy....Pages 45-50
Beta-Blocker Induced Changes in the Cholesterol: HDL-Cholesterol Ratio and Risk of Coronary Heart Disease....Pages 51-61
Lipid-Stoffwechsel unter Beta-Rezeptoren-Blockade — klinische Konsequenzen....Pages 63-72
A Controlled Comparison of the Peripheral Vasoconstrictor Effects of Labetalol with a Conventional Beta-Blocker in Raynaud’s Phenomenon....Pages 73-78
Pharmacokinetic Glossary of Labetalol....Pages 79-83
Front Matter....Pages 85-85
Änderung der Hämodynamik und die Pharmakotherapie des Hochdrucks....Pages 87-102
Haemodynamic Responses to Combined Alpha-Beta-Receptor Blockade with Labetalol in Relation to the Pathophysiological Mechanisms of Hypertension....Pages 103-111
Haemodynamic Stress Reaction in Essential Hypertension and Effect of a Combined α- and β-Blockade....Pages 113-120
Combined Alpha/Beta Blockade with Acebutolol and Prazosin....Pages 121-130
Clinical Pharmacology of Labetalol in Elderly Hypertensives....Pages 131-141
On the Rationale of Combined Alpha/Beta Blockade (Labetalol) in the Treatment of Hypertension in Pregnancy and the Maintenance of Intra-Uterine Fetal Growth....Pages 143-146
Front Matter....Pages 149-149
The Concept of Combined Alpha-Beta-Blockade in Coronary Heart Disease....Pages 151-159
Pathophysiological Mechanisms of Alpha-Adrenoceptor Stimulation in the Ischemic Heart....Pages 161-170
Beta-Adrenoceptor Blockers, Calcium Antagonists and Combined Alpha-Beta-Receptor Blockade in Coronary Heart Disease: Haemodynamic Profiles....Pages 171-177
Oral Beta and Alpha Blockade (Labetalol) in the Management of Stable Angina Pectoris in Normotensive Patients — A Preliminary Report....Pages 179-188
The Use of Labetalol for Acute Myocardial Infarction in Normotensive Patients....Pages 189-196
Front Matter....Pages 149-149
Effects of Alpha-Beta Blockade on Cardiac Performance in Hypertension Complicating Myocardial Infarction....Pages 197-205
Back Matter....Pages 211-216