Arterial Chemoreception: From Molecules to Systems

Front Matter....Pages i-xxiv
The Role of Hypoxia-Inducible Factors in Oxygen Sensing by the Carotid Body....Pages 1-5
Neuronal Mechanisms of Oxygen Chemoreception: An Invertebrate Perspective....Pages 7-17
Peripheral Chemoreceptors in Air- Versus Water- Breathers....Pages 19-27
Sex-Specific Effects of Daily Gavage with a Mixed Progesterone and Glucocorticoid Receptor Antagonist on Hypoxic Ventilatory Response in Newborn Rats....Pages 29-35
Age-Dependent Changes in Breathing Stability in Rats....Pages 37-41
Dose Dependent Effect of Progesterone on Hypoxic Ventilatory Response in Newborn Rats....Pages 43-48
Postnatal Hyperoxia Impairs Acute Oxygen Sensing of Rat Glomus Cells by Reduced Membrane Depolarization....Pages 49-54
Erythropoietin and the Sex-Dimorphic Chemoreflex Pathway....Pages 55-62
Time-Course of Ventilation, Arterial and Pulmonary CO 2 Tension During CO 2 Increase in Humans....Pages 63-70
Oxygen Sensitive Synaptic Neurotransmission in Anoxia-Tolerant Turtle Cerebrocortex....Pages 71-79
Ion Channel Regulation by the LKB1-AMPK Signalling Pathway: The Key to Carotid Body Activation by Hypoxia and Metabolic Homeostasis at the Whole Body Level....Pages 81-90
Anoxia Response in Physiological Potassium of the Isolated Inspiratory Center in Calibrated Newborn Rat Brainstem Slices....Pages 91-98
Hypoxic Redistribution of Iron and Calcium in the Cat Glomus Cells....Pages 99-103
Acute Hypoxia Does Not Influence Intracellular pH in Isolated Rat Carotid Body Type I Cells....Pages 105-107
Hydrogen Sulfide (H 2 S): A Physiologic Mediator of Carotid Body Response to Hypoxia....Pages 109-113
The Retrotrapezoid Nucleus and Breathing....Pages 115-122
The Interaction Between Low Glucose and Hypoxia in the in vitro , Rat Carotid Body....Pages 123-127
Do the Carotid Bodies Modulate Hypoglycemic Counterregulation and Baroreflex Control of Blood Pressure In Humans?....Pages 129-135
Shifting from Hypoxia to Hyperoxia to Assess the Peripheral Chemosensory Drive of Ventilation....Pages 137-142
CO 2 Signaling in Chemosensory Neuroepithelial Cells of the Zebrafish Gill Filaments: Role of Intracellular Ca 2+ and pH....Pages 143-148
Hyperplasia of Pulmonary Neuroepithelial Bodies (NEB) in Lungs of Prolyl Hydroxylase −1(PHD-1) Deficient Mice....Pages 149-155
Precision-Cut Vibratome Slices Allow Functional Live Cell Imaging of the Pulmonary Neuroepithelial Body Microenvironment in Fetal Mice....Pages 157-166
Oxygen Sensitivity of Gill Neuroepithelial Cells in the Anoxia-Tolerant Goldfish....Pages 167-172
Interaction of Hypoxia and Core Temperature: Potential Role of TRPV1....Pages 173-178
Neonatal Intermittent Hypoxia Induces Persistent Alteration of Baroreflex in Adult Male Rats....Pages 179-183
LPS-Induced c-Fos Activation in NTS Neurons and Plasmatic Cortisol Increases in Septic Rats Are Suppressed by Bilateral Carotid Chemodenervation....Pages 185-190
Developmental Regulation of Glucosensing in Rat Adrenomedullary Chromaffin Cells: Potential Role of the K ATP Channel....Pages 191-198
Contribution of Inflammation on Carotid Body Chemosensory Potentiation Induced by Intermittent Hypoxia....Pages 199-205
Spexin Is Expressed in the Carotid Body and Is Upregulated by Postnatal Hyperoxia Exposure....Pages 207-213
Cyclic AMP and Epac Contribute to the Genesis of the Positive Interaction Between Hypoxia and Hypercapnia in the Carotid Body....Pages 215-223
Interactions Between Postnatal Sustained Hypoxia and Intermittent Hypoxia in the Adulthood to Alter Brainstem Structures and Respiratory Function....Pages 225-231
Brain-Derived Neurotrophic Factor in the Nucleus Tractus Solitarii Modulates Glucose Homeostasis After Carotid Chemoreceptor Stimulation in Rats....Pages 233-239
Hydrogen Sulfide Acting at the Carotid Body and Elsewhere in the Organism....Pages 241-247
Purinergic Modulation of Carotid Body Glomus Cell Hypoxia Response During Postnatal Maturation in Rats....Pages 249-253
Serotonin Dynamics and Actions in the Rat Carotid Body: Preliminary Findings....Pages 255-263
Human Carotid Body HIF and NGB Expression During Human Development and Aging....Pages 265-271
Propranolol Does Not Affect the Hindlimb Vasodilatation Elicited by Stimulation of Superior Laryngeal Nerve Paraganglia....Pages 273-277
ATP Release from the Carotid Bodies of DBA/2J and A/J Inbred Mouse Strains....Pages 279-285
Effect of Oxygen on Phosphodiesterases (PDE) 3 and 4 Isoforms and PKA Activity in the Superior Cervical Ganglia....Pages 287-294
Chronic Intermittent Hypoxia Alters Genioglossus Motor Unit Discharge Patterns in the Anaesthetized Rat....Pages 295-300
Upregulation of Pituitary Adenylate Cyclase Activating Polypeptide and Its Receptor Expression in the Rat Carotid Body in Chronic and Intermittent Hypoxia....Pages 301-306
Rabbit Ventilatory Responses to Peripheral Chemoexcitators: Effects of Chronic Hypoxia....Pages 307-313
Effect of Chronic Caffeine Intake on Carotid Body Catecholamine Dynamics in Control and Chronically Hypoxic Rats....Pages 315-323
Effects of Cigarette Smoke and Chronic Hypoxia on Ventilation in Guinea Pigs. Clinical Significance....Pages 325-332
Some Reflections on Intermittent Hypoxia. Does it Constitute the Translational Niche for Carotid Body Chemoreceptor Researchers?....Pages 333-342
Role of Central/Peripheral Chemoreceptors and Their Interdependence in the Pathophysiology of Sleep Apnea....Pages 343-349
Physiologic Basis for Intermittent Hypoxic Episodes in Preterm Infants....Pages 351-358
Chronic Intermittent Hypoxia Increases Apnoea Index in Sleeping Rats....Pages 359-363
Contribution of TASK-Like Potassium Channels to the Enhanced Rat Carotid Body Responsiveness to Hypoxia....Pages 365-371
Antioxidation and the Hypoxic Ventilatory Response....Pages 373-380
Differential Regulation of Tyrosine Hydroxylase by Continuous and Intermittent Hypoxia....Pages 381-385
Heart Failure and Carotid Body Chemoreception....Pages 387-395
Back Matter....Pages 397-406