Applied Physiology in Intensive Care Medicine 1: Physiological Notes - Technical Notes - Seminal Studies in Intensive Care

Front Matter....Pages i-xxii
Front Matter....Pages 1-2
Intrinsic (or auto-) PEEP during controlled mechanical ventilation....Pages 3-5
Intrinsic (or auto-) positive end-expiratory pressure during spontaneous or assisted ventilation....Pages 7-9
Work of breathing....Pages 11-14
Interpretation of airway pressure waveforms....Pages 15-16
Measurement of respiratory system resistance during mechanical ventilation....Pages 17-20
Understanding wasted/ineffective efforts in mechanically ventilated COPD patients using the Campbell diagram....Pages 21-24
Is there an optimal breath pattern to minimize stress and strain during mechanical ventilation?....Pages 25-29
Dead space....Pages 31-34
The multiple inert gas elimination technique (MIGET)....Pages 35-42
Alveolar ventilation and pulmonary blood flow: the $$\\dot{\\rm V}_{\\rm A}/\\dot{\\rm Q}$$ concept....Pages 43-46
Mechanisms of hypoxemia....Pages 47-49
Pulse oximetry....Pages 51-54
Effects of body temperature on blood gases....Pages 55-58
Venous oximetry....Pages 59-61
Relation between PaO 2 /F I O 2 ratio and F I O 2 : a mathematical description....Pages 63-66
Hypoxemia due to increased venous admixture: influence of cardiac output on oxygenation....Pages 67-70
A critique of Stewart’s approach: the chemical mechanism of dilutional acidosis....Pages 71-78
Pulmonary vascular resistance....Pages 79-82
Pulmonary artery occlusion pressure....Pages 83-86
Clinical significance of pulmonary artery occlusion pressure....Pages 87-90
Front Matter....Pages 1-2
Pulmonary capillary pressure....Pages 91-94
Ventricular interdependence: how does it impact on hemodynamic evaluation in clinical practice?....Pages 95-97
Cyclic changes in arterial pressure during mechanical ventilation....Pages 99-102
Left ventricular rotation: a neglected aspect of the cardiac cycle....Pages 103-110
Lactic acidosis....Pages 111-114
Defining acute renal failure: physiological principles....Pages 115-119
Hypotension during intermittent hemodialysis: new insights into an old problem....Pages 121-125
Intracranial pressure....Pages 127-130
Intracranial pressure....Pages 131-134
Neuromonitoring in the intensive care unit. Part I. Intracranial pressure and cerebral blood flow monitoring....Pages 135-143
Neuromonitoring in the intensive care unit. Part II. Cerebral oxygenation monitoring and microdialysis....Pages 145-151
The relationship between the intracranial pressure–volume index and cerebral autoregulation....Pages 153-156
Front Matter....Pages 157-158
A new automated method versus continuous positive airway pressure method for measuring pressure–volume curves in patients with acute lung injury....Pages 159-164
Bedside estimation of recruitable alveolar collapse and hyperdistension by electrical impedance tomography....Pages 165-170
Cuff-leak test for the diagnosis of upper airway obstruction in adults: a systematic review and meta-analysis....Pages 171-179
Reproduction of inert gas and oxygenation data: a comparison of the MIGET and a simple model of pulmonary gas exchange....Pages 181-188
Performance of different continuous positive airway pressure helmets equipped with safety valves during failure of fresh gas supply....Pages 189-193
Validation of Bohr dead space measured by volumetric capnography....Pages 195-199
Lithium dilution cardiac output measurement in the critically ill patient: determination of precision of the technique....Pages 201-207
Tracking changes in cardiac output: methodological considerations for the validation of monitoring devices....Pages 209-216
Front Matter....Pages 157-158
The influence of the airway driving pressure on pulsed pressure variation as a predictor of fluid responsiveness....Pages 217-224
Diagnostic accuracy of passive leg raising for prediction of fluid responsiveness in adults: systematic review and meta-analysis of clinical studies....Pages 225-233
Fluid responsiveness predicted by noninvasive Bioreactance-based passive leg raise test....Pages 235-241
Comparison of cardiac output and blood volumes in intrathoracic compartments measured by ultrasound dilution and transpulmonary thermodilution methods....Pages 243-247
In vivo accuracy of two intraparenchymal intracranial pressure monitors....Pages 249-253
Effect of tidal volume, intrathoracic pressure, and cardiac contractility on variations in pulse pressure, stroke volume, and intrathoracic blood volume....Pages 255-262
Front Matter....Pages 263-264
Manipulating afterload for the treatment of acute heart failure....Pages 265-268
Nosocomial pneumonia....Pages 269-275
The introduction of positive endexpiratory pressure into mechanical ventilation: a retrospective....Pages 277-280
Elastic pressure-volume curves in acute lung injury and acute respiratory distress syndrome....Pages 281-288
The concept of “baby lung”....Pages 289-297
The effects of anesthesia and muscle paralysis on the respiratory system....Pages 299-307
Diaphragmatic fatigue during sepsis and septic shock....Pages 309-315
The use of severity scores in the intensive care unit....Pages 317-322
Oxygen transport— the oxygen delivery controversy....Pages 323-329
Organ dysfunction during sepsis....Pages 331-342
Ventilator-induced lung injury: from the bench to the bedside....Pages 343-352
Remembrance of weaning past: the seminal papers....Pages 353-361
Interactions between respiration and systemic hemodynamics. Part I: basic concepts....Pages 363-372
Interactions between respiration and systemic hemodynamics. Part II: practical implications in critical care....Pages 373-380
Front Matter....Pages 263-264
Systemic and microcirculatory responses to progressive hemorrhage....Pages 381-389
Fluid resuscitation influences cardiovascular performance and mortality in a murine model of sepsis....Pages 391-397
Modeling the effect of time-dependent exposure on intensive care unit mortality....Pages 399-405
Impact of acute hypercapnia and augmented positive end-expiratory pressure on right ventricle function in severe acute respiratory distress syndrome....Pages 407-415
Goal-directed therapy in high-risk surgical patients: a 15-year follow-up study....Pages 417-422
Time course of organ failure in patients with septic shock treated with hydrocortisone: results of the Corticus study....Pages 423-430
Back Matter....Pages 431-435