Application of Hyperthermia in the Treatment of Cancer

Front Matter....Pages I-XII
The Concept of Thermal Dose....Pages 1-6
Aspects of Metabolic Change After Hyperthermia....Pages 7-16
Hyaluronic Acid Degradation Mediated by Thiols and Effects of Hyperthermic Conditions....Pages 17-21
Glutathione Level in Melanoma Cells and Tissue....Pages 22-26
Changes of Plasma Acetate Levels in Whole-Body Hyperthermia....Pages 27-31
Physiological Effects of Hyperthermia....Pages 32-43
Hyperthermia-Induced Changes in Tumor Microcirculation....Pages 44-59
Changes in Tumor Vasculature Under Fractionated Radiation — Hyperthermia Treatment....Pages 60-64
Pathophysiology of Tumors in Hyperthermia....Pages 65-75
Technical Aspects of Hyperthermia....Pages 76-86
Advanced Technique in Localized Current Field Hyperthermia....Pages 87-92
A 500-kHz Localized Current Field Hyperthermia System for Use with Ophthalmic Plaque Radiotherapy....Pages 93-98
Simulation of Interstitial Microwave Hyperthermia Using the Finite Element Method....Pages 99-103
Some Basic Effects in Cellular Thermobiology....Pages 104-112
Growth, Cell Proliferation and Morphological Alterations of a Mouse Mammary Carcinoma After Exposure to X-Rays and Hyperthermia....Pages 113-117
Analysis of Results in Neck Node Metastases from Tumors of the Head and Neck....Pages 118-122
Two Versus Six Hyperthermia Treatments in Combination with Radical Irradiation for Fixed Metastatic Neck Nodes: Progress Report....Pages 123-128
First Results After Hyperthermia Treatment with the BSD System in Essen....Pages 129-135
Interstitial Radiotherapy Combined with Interstitial Hyperthermia in the Management of Recurrent Tumors....Pages 136-140
Localized, Non-Invasive Deep Microwave Hyperthermia for the Treatment of Prostatic Tumors: The First 5 Years....Pages 141-146
External Microwave Hyperthermia Combined with Radiation Therapy for Extensive Superficial Chest Wall Recurrences....Pages 147-151
Microwave-Induced Hyperthermia and Radiotherapy in Human Superficial Tumours: Clinical Results with a Comparative Study of Combined Treatment Versus Radiotherapy Alone....Pages 152-156
Interaction of Hyperthermia and Chemotherapy....Pages 157-169
Thermostability of Cytostatic Drugs in Vitro and Thermosensitivity of Cultured Human Lymphoblasts Against Cytostatic Drugs....Pages 170-176
A Rapid in Vitro Assay for Predicting Thermochemosensitivity of Human Cancer: Comparison with Clonogenic Assay....Pages 177-183
The Cytotoxic and Bleomycin-Sensitizing Effect of Hyperthermia on Different Cell Lines....Pages 184-187
Pilot Studies of Microwave-Induced Brain Hyperthermia and Systemic BCNU in a Rat Glioblastoma Model....Pages 188-192
Pharmacokinetics of Methotrexate During Regional Hyperthermia in a Pig Model....Pages 193-199
Summary of Recent Clinical Experience in Whole-Body Hyperthermia Combined with Chemotherapy....Pages 200-204
Coagulation and Fibrinogenolysis During Whole-Body Hyperthermia....Pages 205-208
Treatment of Superficial Neoplastic Lesions Using Hyperthermia, Radiotherapy and Chemotherapy....Pages 209-213
Clinical Experience in the Combination of Hyperthermia with Chemotherapy or Radiotherapy....Pages 214-221
Combined Treatment of Advanced Bladder Carcinoma....Pages 222-225
Experience with an Annular Phased Array Hyperthermia System in the Treatment of Advanced Recurrences of the Pelvis....Pages 226-235
Regional Hyperthermia Combined with Systemic Chemotherapy in Advanced Abdominal and Pelvic Tumors: First Results of a Pilot Study Employing an Annular Phased Array Applicator....Pages 236-243
Deep Microwave Hyperthermia for Metastatic Tumors of the Liver....Pages 244-248
Future Trends in Heating Technology of Deep-Seated Tumors....Pages 249-262
Percutaneous Placement of Catheters for Temperature Measurement During Hyperthermia....Pages 263-266
CT-Guided Placement of Temperature Probes in Pulmonary Cancer....Pages 267-271
Back Matter....Pages 272-277