Apicomplexan Parasites: Molecular Approaches toward Targeted Drug Development (Drug Discovery in Infectious Diseases)

Contents......Page p0006.djvu
Foreword......Page p0009.djvu
Preface......Page p0011.djvu
List of Contributors......Page p0013.djvu
Part One......Page p0022.djvu
Drug Discovery Approaches Toward Anti-Parasitic Agents......Page p0023.djvu
New Bioinformatic Strategies Against Apicomplexan Parasites......Page p0041.djvu
Sorting Potential Therapeutic Targets in Apicomplexa......Page p0054.djvu
Alternatives to Drug Development in the Apicomplexa......Page p0071.djvu
Part Two ......Page p0092.djvu
Energy Metabolism as an Antimalarial Drug Target......Page p0093.djvu
Polyamines in Apicomplexan Parasites......Page p0112.djvu
The Reducing Milieu of Parasitized Cells as a Targetof Antimalarial Agents: Methylene Blue as an Ethical Drug......Page p0130.djvu
Lipids as Drug Targets for Malaria Therapy......Page p0152.djvu
Targeting Apicoplast Pathways in Plasmodium......Page p0178.djvu
Lipoic Acid Acquisition and Glutathione Biosynthesisin Apicomplexan Parasites......Page p0202.djvu
Antimalarial Drugs and Molecules InhibitingHemozoin Formation......Page p0219.djvu
Exploiting the Vitamin Metabolism of Apicomplexaas Drug Targets......Page p0249.djvu
Vitamin Biosynthetic Pathways, the PLP Synthase Complex,and the Potential for Targeting Protein–Protein Interaction......Page p0264.djvu
Targeting Prokaryotic Enzymes in the Eukaryotic PathogenCryptosporidium......Page p0284.djvu
Part Three......Page p0299.djvu
Novel Apicomplexan Phosphatases and Immunophilinsas Domain-Specific Drug Targets......Page p0300.djvu
Dehydrogenases and Enzymes of the Mitochondrial ElectronTransport Chain as Anti-Apicomplexan Drug Targets......Page p0318.djvu
Calcium-Dependent Protein Kinases as Drug Targetsin Apicomplexan Parasites......Page p0330.djvu
Protein Acylation: New Potential Targets for InterventionAgainst the Apicomplexa......Page p0345.djvu
Drugs and Drug Targets in Neospora caninumand Related Apicomplexans......Page p0368.djvu
Part Four......Page p0381.djvu
Subversive Substrates of Glutathione Reductases fromPlasmodium falciparum-Infected Red Blood Cells asAntimalarial Agents......Page p0382.djvu
Ferroquine: A Concealed Weapon......Page p0404.djvu
Current Aspects of Endoperoxides in Antiparasitic Chemotherapy......Page p0419.djvu
Plasmodium Hsp90 as an Antimalarial Target......Page p0437.djvu
Drug Discovery Against Babesia and Toxoplasma......Page p0458.djvu
Search for Drugs and Drug Targets against Babesia bovis,Babesia bigemina, Babesia caballi, and Babesia (Theileria) equi......Page p0473.djvu
Orlistat: A Repositioning Opportunity as a Growth Inhibitorof Apicomplexan Parasites?......Page p0485.djvu
Recent Drug Discovery Against Cryptosporidium......Page p0497.djvu
Index......Page p0517.djvu