Animal Models of Human Disease

Content: 
Copyright
Page iv

Contributors
Pages xi-xiii

Preface
Page xv
Karen T. Chang, Kyung-Tai Min

Chapter 1 - Modeling Human Prostate Cancer in Genetically Engineered Mice
Pages 1-49
Fen Wang

Chapter 2 - Modeling Cancers in Drosophila
Pages 51-82
Cédric Polesello, Fernando Roch, Vanessa Gobert, Marc Haenlin, Lucas Waltzer

Chapter 3 - Probing Human Cardiovascular Congenital Disease Using Transgenic Mouse Models
Pages 83-110
Paige Snider, Simon J. Conway

Chapter 4 - Dissection of Cardiovascular Development and Disease Pathways in Zebrafish
Pages 111-153
Joanne Chan, John D. Mably

Chapter 5 - Drosophila Models of Cardiac Disease
Pages 155-210
Nicole Piazza, R.J. Wessells

Chapter 6 - Animal Models of Retinal Disease
Pages 211-286
Erica L. Fletcher, Andrew I. Jobling, Kirstan A. Vessey, Chi Luu, Robyn H. Guymer, Paul N. Baird

Chapter 7 - Toward a Better Understanding of Human Eye Disease: Insights From the Zebrafish, Danio rerio
Pages 287-330
Jonathan Bibliowicz, Rachel K. Tittle, Jeffrey M. Gross

Chapter 8 - 800 Facets of Retinal Degeneration
Pages 331-368
T. Cook, A. Zelhof, M. Mishra, J. Nie

Chapter 9 - Animal Models of Glycogen Storage Disorders
Pages 369-388
H. Orhan Akman, Adithya Raghavan, William J. Craigen

Chapter 10 - Modeling Disorders of Fatty Acid Metabolism in the Mouse
Pages 389-417
Eric S. Goetzman

Chapter 12 - Demise of the Flies: Why Drosophila Models Still Matter
Pages 483-498
Mathieu F. Bakhoum, George R. Jackson

Chapter 11 - Genetic Mouse Models of Neurodegenerative Diseases
Pages 419-482
Alzbeta Trancikova, David Ramonet, Darren J. Moore

Chapter 13 - Watching Worms Whither: Modeling Neurodegeneration in C. elegans
Pages 499-514
Benjamin Wolozin, Christopher Gabel, Andrew Ferree, Maria Guillily, Atsushi Ebata

Index
Pages 515-526