Animal Cell Technology: Basic & Applied Aspects: Proceedings of the Fifteenth Annual Meeting of the Japanese Association for Animal Cell Technology (JAACT), Fuchu, Japan, November 11–15, 2002

Front Matter....Pages i-xiii
Recombinant expression of human collagens....Pages 1-5
Expression Profiling of Parietal Endoderm Cells and Development of Systems for Large Scale Production of Laminins....Pages 7-11
Synthetic Peptides from Laminin for Tissue Engineering....Pages 13-17
A Novel Technology for Conversion of In Vivo Tissue Architecture into a Three-Dimensional In Vitro Culture Mode....Pages 19-23
Construction of Liver Model with Genetically Engineered Human HepG2 Cells....Pages 25-29
Determinants of Ligand Specificity in Groups I and IV WW domains....Pages 31-35
Role of the WW Domain in Signaling and Disease....Pages 37-41
Structural Biology of Signal Transduction Mediated by Grb2....Pages 43-47
Modulation of Leukocyte Function by Food Factors....Pages 49-53
Anticancer Effects of Lignans....Pages 55-58
Effect of Sulfur-Containing Active Principles in Garlic on the Physiological Function of Hepatocytes....Pages 59-63
Suppression of Free Radical-Induced Mutation of Animal Cell Genes by Food Factors....Pages 65-69
Chemoenzymatic Approaches for the Preparation of Oligosaccharides and Glycopeptides....Pages 71-75
Cell Growth Arrest by Nucleotides as a Tool for Improved Production of Biopharmaceuticals....Pages 77-81
Transient Gene Expression: A Novel Mammalian Cell-Based Technology for Recombinant Protein Production....Pages 83-88
Optimization of the Production of Retroviral Vectors....Pages 89-97
Effects of Glucose and CO 2 Concentrations on CHO Cell Physiology....Pages 99-103
Suppression of glutamate-induced neural cell death by electrolyzed-reduced water....Pages 105-109
Development of Apoptosis-Resistant Dihydrofolate Reductase-Deficient Chinese Hamster Ovary Cell Line....Pages 111-115
High Expression of Human Monoclonal Antibodies in CHO Cells Selected Using a Cycloheximide Resistance Marker....Pages 117-120
Development of a Serum-Free Medium Supplemented with Hydrolysate for the Suspension Culture of Recombinant CHO Cells Producing Human Thrombopoietin....Pages 121-125
Effect of Growth Factors and Ascorbic Acid 2-Phosphate on Liver Specific Functions of Porcine Hepatocytes....Pages 127-131
Culture of Porcine Hepatocytes Using Radial Flow Bioreactor System....Pages 133-137
The Role of Glutamine in Hybridoma Cell Culture....Pages 139-143
Protective Action of Reduced Water Against Alloxan-Induced Cytotoxicity in Pancreatic β-Cell....Pages 145-149
Effect of Doxycycline-Regulated Chaperone Expression on Recombinant Protein Productivity in CHO Cells....Pages 151-155
Biphasic Culture Strategy Based on Hyperosmotic Pressure for Improved Humanized Antibody Production in Chinese Hamster Ovary Cell Culture....Pages 157-161
Effect of Low Culture Temperature on Foreign Protein Production in Recombinant CHO Cells....Pages 163-167
Control of Temperature and pH Enhances Human Monoclonal Antibody Production in CHO Cell Culture....Pages 169-172
Effects of Pluronic F68 on t-PA Producing Chinese Hamster Ovary (CHO) Cells Under Agitating and Static Conditions....Pages 173-177
Structure and Function of Laminin α4 G Domain....Pages 179-183
Introduction of Apoptosis-Resistant Genes to Hybridoma Cells and Their Influence....Pages 185-189
An Engineering Method to High Yielding Production of Recombinant Anti-HIV Monoclonal Antibody Using Generic Multi Feed Fermentation....Pages 191-195
Proliferation and Monoclonal Antibody Production of Hybridoma Cells Immobilized on Non-Woven Polyester Fabric Discs....Pages 197-201
Mass-Production in Yeast of Laminins as the Material of Reconstructive Therapy....Pages 203-206
Effects of Carvacrol on a Human Non-Small Cell Lung Cancer (NSCLC) Cell Line, A549....Pages 207-211
Establishment of Dendritic Cell Line from Caspase-1-Deficient Mice....Pages 213-217
Isolation and Characterization of Fetal Bovine Cells Derived from Liver and Bone Marrow....Pages 219-223
Artificial Selection of High Proliferating and Apoptosisresistant NS0 Cells for Industrial Production Systems....Pages 225-231
Endothelial Cells Culture and Its Use to Produce a Vaccine Against Rickettsiae....Pages 233-236
Monocytes Suppress Immune Responses of Peripheral Blood Lymphocytes: Possible Implication of Immature Dendritic Cells....Pages 237-242
Establishment and Analysis of Germfree T Cell Receptor Transgenic Mice....Pages 243-247
Development of a Novel Process to Produce a Veterinary Rabies Vaccine in BHK-21 Cells Grown on Microcarriers in a 20 Liter Bioreactor....Pages 249-253
Epitope-Specific Suppression of Immune Response Against β -Lactoglobulin Induced by Oral Administration of Cow’s Milk with Heat Treatments....Pages 255-259
Production of Anti-Peptide Antibody by In Vitro Immunization....Pages 261-265
Generation of Mouse-Human Hybridomas Secreting Antibodies Against Peanut Allergens....Pages 267-271
Reduced Immunogenicity of β-Lactoglobulin by Conjugation with Alginic Acid Oligosaccharide....Pages 273-276
Evaluation of the Immuno-Protective Effects of the New-Type of Bags Using ELISA- and FACS-Analysis....Pages 277-280
Effect of Silk Protein Sericin on Hepatoblastoma HepG2 Cells....Pages 281-285
Isolation of Human Mesenchymal Stem Cell-Like Fibroblast from Adipose Tissue for Reconstructive Therapy....Pages 287-292
Change of the Cellular Function by Connexin Gene Transfection in a Hepatoma Cell Line....Pages 293-297
Production of Pharmaceutical Proteins by Transgenic Avian....Pages 299-303
Influence of Serum Concentration on Cell Growth and Retrovirus Production and Decay Kinetics....Pages 305-309
Neural Precursor Cells from Adult Mouse Cerebral Cortex....Pages 311-315
The Inhibition of MMP-2 Expression in Human Fibrosarcoma HT1080 Cells by Electrolyzed-Reduced Water....Pages 317-321
The Role of Plasminogen in the Proliferation of Murine Hepatocytes in Primary Culture....Pages 323-327
Transcriptional Regulation Mechanisms of Telomerase Reverse Transcriptase Gene Responsible for Ubiquitous Expression of Telomerase in Mouse....Pages 329-333
Cell Proliferation Switch Responsive to Fluorescein Dimer....Pages 335-339
Hydrogen Peroxide Triggers Cellular Senescence Programs: Possible Application to Tumor Suppression....Pages 341-345
Essential Role of Cell-Cell Interaction in Primary Hepatocyte Cultures....Pages 347-351
Involvement of Myosin Light Chain in Suppressive Effect of Epigallocatechin-3- O -Gallate on Histamine Release from the Human Basophilic KU812 Cells....Pages 353-357
Proteomic analysis of changes in excitable and non-excitable cells exposed to DC electric fields of physiological strength....Pages 359-362
Inhibition of the Expression of IgE Heavy Chain Germline Transcripts by Peroxisome Proliferator-Activated Receptor-γ Ligands....Pages 363-368
Negative Regulation of the Basophil Activation by Natural Ligands for Peroxisome Proliferator-Activated Receptors....Pages 369-374
Two-Dimensional Electrophoresis of Proteins from Human Intestinal Caco-2 Cells Exposed to the Known Xenoestrogen Nonylphenol....Pages 375-379
The Suppressive Effect of Electrolyzed Reduced Water on Lipid Peroxidation....Pages 381-385
Electrolyzed Reduced Water Induces Differentiation in K-562 Human Leukemia Cells....Pages 387-391
Oral Administration of Soy Isoflavones and Determination of Serum Isoflavone Levels in Sprague-Dawley Rats....Pages 393-397
Effect of β-Casein on Cytokine Production of Mouse Spleen Lymphocytes....Pages 399-404
Changes in the Relevant Test Parameters of 219 Diabetes Patients under the Influence of the So Called “Nordenau - Phenomenon” in the Prospective Observation Procedure....Pages 405-409
Decreased Intracellular Peroxide Levels of Rat Ascites Hepatoma Cells by Resveratrol and Sera from Resveratrol-Treated Rats....Pages 411-415
Inhibitory Effects of Several Flavonoids on Prostaglandin Production and E-Selectin Expression in Cultured Animal Cells....Pages 417-421
Phytoestrogens Enhance the Acetylcholinesterase Activity of the Rat Pheochromocytoma Cell Line PC12 by Binding to the Estrogen Receptor....Pages 423-427
Sericin Protein Derived from Silk Accelerates Proliferation of Mammalian Cells....Pages 429-433
Effect of the Administration of Shark Type I Collagen to Ovariectomized Rats....Pages 435-439
Alginic Acid Oligosaccharide Up-Regulates IFN-γ Production by Lymph Node Cells....Pages 441-445
Actions of Sulfur Amino Acids on Lipase Activities in Cultured Adipocytes....Pages 447-451
Analysis of the Mechanism of the Tight-Junctional Permeability Increase by Capsaicin Treatment on the Intestinal Caco-2 Cell....Pages 453-457
Effect of Shark Skin Collagen on Morphologic and Biochemical Changes in a Guinea Pig Model of Osteoarthritis....Pages 459-463
Inhibitory Effect of Conjugated Linoleic Acid Isomers on the Proliferation of Human Breast Cancer Cells....Pages 465-470
Effects of Carvacrol on Sister Chromatid Exchanges in Human Lymphocyte Cultures....Pages 471-474
Biocompatible Biomaterials for the Human Chondrocyte Differentiation Estimated by RT-PCR Method....Pages 475-479
Different Expression of Gap Junctional Protein Connexin43 in Two Strains of Mice after One-Month Implantation of Poly-L-Lactic Acid....Pages 481-485
Changes on Cell Surface and Microfilament Distribution during Myoblast Differentiation and Transformation In Vitro ....Pages 487-491
Primary Cilium in CO25 Cell Line....Pages 493-497
Environmental Chemicals Affect Nerve Cell Differentiation in SFME Cells through Specific Gene Expression....Pages 499-503
Evaluation of the Cornea Cells Affected by Multi-Purpose Solutions for Contact-Lens....Pages 505-509
Back Matter....Pages 511-518