Amino Acids as Chemical Transmitters

Front Matter....Pages i-xii
Morphological Correlates for Transmitter Synthesis, Transport, Release, Uptake and Catabolism: A Study of Serotonin Neurons in the Nucleus Paragigantocellularis Lateralis....Pages 1-30
Comments on the Morphology of Inhibitory Axons....Pages 31-38
Ultrastructural Analysis of Axo-Dendritic Initial Collateral Terminals of a Feline Spinocervical Tract Neurone, Stained Intracellularly with Horseradish Peroxidase....Pages 39-48
Electron Cytochemistry of GABA-Transaminase in Rat Cerebellar Cortex, and Evidence for Multimolecular Forms of the Enzyme....Pages 49-53
Pre- and Non-Synaptic Activities of GABA and Related Amino Acids in the Mammalian Nervous System....Pages 55-86
Quantitative Studies of Iontophoretically-Applied Excitatory Amino Acids....Pages 87-91
Interactions of Central Depressants with Amino Acids and Their Antagonists....Pages 93-101
Critical Evaluation of the Use of Radioautography as a Tool in the Localization of Amino Acids in the Mammalian Central Nervous System....Pages 103-121
Transmitters in the Basal Ganglia....Pages 123-141
Comments on Localization of Neurotransmitters in the Basal Ganglia....Pages 143-153
Localization of Transmitter Amino Acids: Application to Hippocampus and Septum....Pages 155-171
Glutamate Concentration in Individual Layers of the Rabbit Hippocampus....Pages 173-176
The Effect of Intrahippocampal Administration of γ-Aminobutyric Acid (GABA)....Pages 177-180
Neurotransmitters in the Amygdala: A Brief Review....Pages 181-192
GABA Markers in the Hypothalamus : Topographical Distribution and Origin....Pages 193-212
Identified Aplysia Neurons with Rapid and Specific Glycine Uptake....Pages 213-219
Neurotransmitters in the Avian Visual System....Pages 221-239
Neurotransmitters of the Mammalian Visual System....Pages 241-256
The Localization and Metabolism of Neuroactive Amino Acids in the Retina....Pages 257-274
Light-Induced Release of Amino Acids from the Retina....Pages 275-295
Classification and Location of Neurons Taking Up 3 H-GABA in the Visual Cortex of Rats....Pages 297-303
GABA Agonists and Uptake Inhibitors of Restricted Conformations: Structure-Activity Relations....Pages 305-321
Muscimol Analogues Injected into Substantia Nigra: A Valuable New In Vivo Model for GABA-Ergic Drugs....Pages 323-326
Uptake, Exchange and Release of GABA in Isolated Nerve Endings....Pages 327-350
Cis 3-Aminocyclohexane Carboxylic Acid, a Selective Inhibitor and Substrate for the Neuronal GABA Uptake Process....Pages 351-356
Properties of the Accumulation of D-[ 14 C]Aspartate into Rat Cerebral Crude Synaptosomal Fraction....Pages 357-361
The Effect of Glutamate on the Structure and K + -Transport of Synaptosomes....Pages 363-366
On the Metabolic and Intrasynaptic Origin of Amino Acid Transmitters....Pages 367-377
Glutamate as a CNS Neurotransmitter: Properties of Release, Inactivation and Biosynthesis....Pages 379-412
Role of Gabaergic and Glycinergic Transmissions in the Substantia Nigra in the Regulation of Dopamine Release in the Cat Caudate Nucleus....Pages 413-423
The Interaction between GABA-Ergic Drugs and Dopaminergic Stimulants....Pages 425-430
Glutamate Decarboxylase, Properties and the Synaptic Function of GABA....Pages 431-438
The Possible Involvement of GABA and Its Compartmentation in the Mechanism of Some Convulsant and Anticonvulsant Agents....Pages 439-444
The GABA Receptor Assay: Focus on Human Studies....Pages 445-456
 3 H-GABA Binding to Membranes Prepared from Post-Mortem Human Brain: Pharmacological and Pathological Investigations....Pages 457-466
Studies on the Gamma-Aminobutyric Acid Receptor/Ionophore Proteins in Mammalian Brain....Pages 467-486
Comparison of 3 H-Muscimol and 3 H-GABA Receptor Binding in Rat Brain....Pages 487-492
GABA Receptor in Rat Brain: Demonstration of an Antagonist Binding Site....Pages 493-498
A Study of the GABA Receptor Using 3 H-Bicuculline Methobromide....Pages 499-506
GABA Receptors and Phospholipids....Pages 507-516
Second Messenger Responses and Regulation of High Affinity Receptor Binding to Study Pharmacological Modifications of Gabaergic Transmission....Pages 517-530
Glycine: Inhibition from the Sacrum to the Medulla....Pages 531-570
Taurine and other Sulfur containing Amino Acids: Their Function in the Central Nervous System....Pages 571-597
A Functional Role for Amino Acids in the Adaptation of Tissues from the Nervous System to Alterations in Environmental Osmolality....Pages 599-627
Isolation and Biochemical Characterization of Morphologically Defined Structures, Including Cell Types, from the Cerebellum....Pages 629-651
Glial Cells and Amino Acid Transmitters....Pages 653-662
Interactions between Neurotransmitters and Astroglial Cells....Pages 663-668
Amino Acid Precursors: Their Transport into Brain and Initial Metabolism....Pages 669-689
Metabolic Compartmentation of the Glutamate - Glutamine System: Glial Contribution....Pages 691-708
Compartmentation of Amino Acids in Brain: The GABA-Glutamine-Glutamate Cycle....Pages 709-723
Computer Modeling as an Aid to Understanding Metabolic Compartmentation of the Krebs Cycle in Brain Tissue....Pages 725-738
Back Matter....Pages 739-747