African Horse Sickness

Front Matter....Pages I-VIII
Front Matter....Pages 1-1
Taxonomy of African horse sickness viruses....Pages 3-11
Epidemiology of African horse sickness and the role of the zebra in South Africa....Pages 13-19
Transmission and distribution of African horse sickness virus serotypes in South African zebra....Pages 21-28
Serological and virological responses in mules and donkeys following inoculation with African horse sickness virus serotype 4....Pages 29-36
Donkeys as reservoirs of African horse sickness virus....Pages 37-47
Clinical, virological and immune responses of normal and immunosuppressed donkeys (Equus asinus africanus) after inoculation with African horse sickness virus....Pages 49-56
Immunohistochemical demonstration of African horse sickness viral antigen in tissues of experimentally infected equines....Pages 57-65
Front Matter....Pages 67-67
The 1996 outbreak of African horse sickness in South Africa — the entomological perspective....Pages 69-83
The seasonal and geographical distribution of Culicoides imicola , C. pulicaris group and C. obsoletus group biting midges in central and southern Spain....Pages 85-91
The relationship between climate and the distribution of Culicoides imicola in Iberia....Pages 93-102
Simulation studies of African horse sickness in Spain....Pages 103-111
The Culicoides vectors of African horse sickness virus in Morocco: distribution and epidemiological implications....Pages 113-125
Studies of the mortality rate of Culicoides imicola in Morocco....Pages 127-136
Modelling the distribution and abundance of Culicoides imicola in Morocco and Iberia using climatic data and satellite imagery....Pages 137-153
Effect of temperature on African horse sickness virus infection in Culicoides ....Pages 155-163
Duration of repellency of various synthetic and plant-derived preparations for Culicoides imicola , the vector of African horse sickness virus....Pages 165-174
Front Matter....Pages 175-175
New generation of African horse sickness virus vaccines based on structural and molecular studies of the virus particles....Pages 177-202
Expression of the major core structural proteins VP3 and VP7 of African horse sickness virus, and production of core-like particles....Pages 203-209
VP7 from African horse sickness virus serotype 9 protects mice against a lethal, heterologous serotype challenge....Pages 211-219
Molecular epidemiology of African horse sickness virus based on analyses and comparisons of genome segments 7 and 10....Pages 221-234
Front Matter....Pages 175-175
Structural studies of orbivirus particles....Pages 235-250
Characterization of two African horse sickness virus nonstructural proteins, NS1 and NS3....Pages 251-258
Development of a mouse model system, coding assignments and identification of the genome segments controlling virulence of African horse sickness virus serotypes 3 and 8....Pages 259-279
Phylogenetic analysis of African horse sickness virus segment 10: sequence variation, virulence characteristics and cell exit....Pages 281-293
Front Matter....Pages 295-295
Future international management of African horse sickness vaccines....Pages 297-304
Application of an indirect fluorescent antibody assay for the detection of African horse sickness virus antibodies....Pages 305-310
Validation of ELISA for the detection of African horse sickness virus antigens and antibodies....Pages 311-315
Use of reverse transcriptase-polymerase chain reaction (RT-PCR) and dot-blot hybridisation for the detection and identification of African horse sickness virus nucleic acids....Pages 317-327
Western immunoblotting as a method for the detection of African horse sickness virus protein-specific antibodies: Differentiation between infected and vaccinated horses....Pages 329-336
Conclusions and recommendations of the meeting....Pages 337-342
Back Matter....Pages 343-344