Advances in Pain Research: Mechanisms and Modulation of Chronic Pain

Front Matter ....Pages i-x
 Molecular Mechanisms of the Sense of Touch: An Overview of Mechanical Transduction and Transmission in Merkel Discs of Whisker Hair Follicles and Some Clinical Perspectives  (Jianguo G. Gu)....Pages 1-12
 TRP Channels in Nociception and Pathological Pain  (Chen-Yu Hung, Chun-Hsiang Tan)....Pages 13-27
 Involvement of TRPV1-ANO1 Interactions in Pain-Enhancing Mechanisms  (Y. Takayama, Makoto Tominaga)....Pages 29-36
 Roles of ASICs in Nociception and Proprioception  (Cheng-Han Lee, Chih-Cheng Chen)....Pages 37-47
 Tackling Pain Associated with Rheumatoid Arthritis: Proton-Sensing Receptors  (Wei-Hsin Sun, Shih-Ping Dai)....Pages 49-64
 Advances in Experimental Medicine and Biology: Intrafascicular Local Anesthetic Injection Damages Peripheral Nerve-Induced Neuropathic Pain  (Kuang-Yi Tseng, Hung-Chen Wang, Lin-Li Chang, Kuang-I Cheng)....Pages 65-76
 Microglia in the CNS and Neuropathic Pain  (Makoto Tsuda)....Pages 77-91
 Descending Noradrenergic Inhibition: An Important Mechanism of Gabapentin Analgesia in Neuropathic Pain  (Ken-ichiro Hayashida, James C. Eisenach)....Pages 93-100
 Chronic Neuropathic Pain Protects the Heart from Ischemia-Reperfusion Injury  (Yi-Fen Cheng, Chien-Chang Chen)....Pages 101-114
 Knowing the Neuronal Mechanism of Spontaneous Pain to Treat Chronic Pain in the Future  (Xiang-Yao Li, Jing-Hua Wang, Cheng Wu)....Pages 115-124
 Role of Neuroinflammation in Opioid Tolerance: Translational Evidence from Human-to-Rodent Studies  (Chih-Peng Lin, Dai-Hua Lu)....Pages 125-139
 Neural Mechanisms of Offset Analgesia  (Jiro Kurata)....Pages 141-146
 Cortical LTP: A Synaptic Model for Chronic Pain  (Min Zhuo)....Pages 147-155
 Pain-Associated Neural Plasticity in the Parabrachial to Central Amygdala Circuit  (Fusao Kato, Yae K. Sugimura, Yukari Takahashi)....Pages 157-166
 Electrophysiological Signature of Pain  (Zi-Fang Zhao, You Wan)....Pages 167-177
 Neuroimaging Studies of Primary Dysmenorrhea  (Intan Low, Shyh-Yuh Wei, Pin-Shiuan Lee, Wei-Chi Li, Lin-Chien Lee, Jen-Chuen Hsieh et al.)....Pages 179-199
 Brain Reward Circuit and Pain  (Moe Watanabe, Minoru Narita)....Pages 201-210
 Involvement of P2X7 Receptors and BDNF in the Pathogenesis of Central Poststroke Pain  (Yung-Hui Kuan, Hsi-Chien Shih, Bai-Chuang Shyu)....Pages 211-227
 Melatonin: A New-Generation Therapy for Reducing Chronic Pain and Improving Sleep Disorder-Related Pain  (Tavleen Kaur, Bai-Chuang Shyu)....Pages 229-251
 Central Poststroke Pain, Comorbidity, and Associated Symptoms in Animal and Human Models  (Bai-Chuang Shyu, Andrew Chih Wei Huang)....Pages 253-265