Advances in Osteoarthritis

Front Matter....Pages II-X
Front Matter....Pages 1-1
Extracellular Ions and Hydrostatic Pressure: Their Influence on Chondrocyte Intracellular Ionic Composition....Pages 3-20
Cytoskeleton and Proteoglycan Synthesis in Chondrocytes Under Hydrostatic Pressure....Pages 21-34
Cyclic Tensile Stretch Inhibits Proteoglycan Synthesis by Downregulating Protein Kinase C Activity....Pages 35-47
Muscarinic Receptor-Mediated Ca 2+ Control, Protein Kinase C Activity, and Proteoglycan Release and Synthesis in Articular Chondrocytes....Pages 48-55
Front Matter....Pages 57-57
Physical Diagnostics of Cartilage Degeneration....Pages 59-73
Applications of MRI for Evaluating Osteoarthritis....Pages 74-92
Development of Quantitative Magnetic Resonance Imaging for Assessment of Cartilage Damage and Repair in Vivo....Pages 93-106
Gene Delivery to Chondrocytes Using Adenovirus Vector....Pages 107-118
Front Matter....Pages 119-119
The Recently Discovered Collagenase-3: A Key Role in Osteoarthritis....Pages 121-133
Calpain and Its Role in Arthritis....Pages 134-141
Immunohistochemical Localization of Cartilage-Specific and Non-Cartilage-Specific Proteoglycans in Experimental Osteoarthritic Articular Cartilage in Rats....Pages 142-150
Front Matter....Pages 151-151
Results of a Phase II Rheumatoid Arthritis Clinical Trial Using T-Cell Receptor Peptides....Pages 153-162
Chondroprotective Activity of a Matrix Metalloprotease Inhibitor, CGS 27023A, in Animal Models of Osteoarthritis....Pages 163-173
Protein Kinase C-Activator Inhibits Progression of Osteoarthritis by Inhibiting c-Fos Protein Expression in Articular Chondrocytes....Pages 174-184
Front Matter....Pages 185-185
Articular Cartilage Repair....Pages 187-202
Knee Washout for Osteoarthritis....Pages 203-212
Viscosupplementation for the Treatment of Osteoarthritis of the Knee with Hyaluronan and Hylans: Rationale and State of the Art....Pages 213-236
Effects of Sodium Hyaluronic Acid on Fibrinolytic Factors in Humans with Arthropathies....Pages 237-250
Front Matter....Pages 251-251
Thigh Pain After Total Hip Arthroplasty....Pages 253-270
Polyethylene Properties and Their Role in Osteolysis After Total Joint Arthroplasty....Pages 271-285
Front Matter....Pages 251-251
Responses in the Underlying Bone During Migration of Hydroxyapatite Grafts in the Growing Rabbit....Pages 286-296
Back Matter....Pages 297-298