Advances in Nitrate Therapy

Front Matter....Pages I-VI
Front Matter....Pages 1-1
Introduction....Pages 3-5
The Mechanism of Action of Nitrates at the Cellular Level....Pages 6-7
Front Matter....Pages 9-9
Stable Angina Pectoris....Pages 11-13
The Mechanism of Action of Nitrates in Angina Pectoris....Pages 14-20
Nitrates Compared and Combined with Other Antianginal Drugs....Pages 21-29
Unstable Angina Pectoris....Pages 30-34
Long-Term Use of Nitrates in Angina Pectoris....Pages 35-42
Silent Ischemia....Pages 43-44
Acute Myocardial Infarction....Pages 45-51
Congestive Heart Failure....Pages 52-56
Congestive Heart Failure and Valvular Diseases....Pages 57-59
Long-Term Nitrate Therapy in Congestive Heart Failure....Pages 60-62
Nitrates Combined and Compared with Other Drugs in Congestive Heart Failure....Pages 63-68
Systemic Hypertension, Arrhythmias and Cardiac Surgery....Pages 69-72
Pulmonary, Abdominal, and Peripheral Vascular Effects....Pages 73-76
Non-Cardiovascular Indications for Nitrates....Pages 77-78
Nitrates in Children and the Elderly....Pages 79-82
Front Matter....Pages 83-83
Sublingual Tablets and Oral Spray....Pages 85-90
Intravenous Administration of Nitrates....Pages 91-91
Intracoronary Administration of Nitrates....Pages 92-95
Front Matter....Pages 83-83
Oral Administration of Nitrates....Pages 96-98
Mononitrates....Pages 99-110
Transdermal Administration of Nitrates....Pages 111-127
Buccal Nitroglycerin....Pages 128-129
Front Matter....Pages 131-131
Clinical Pharmacology....Pages 133-142
Side Effects and Drug Interactions....Pages 143-148
Dosage and Administration....Pages 149-153
Conclusions....Pages 155-155
Back Matter....Pages 157-185