Advances in Myocardiology: Volume 4

Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Pathogenesis and Prophylaxis of Cardiac Lesions in Stress....Pages 3-21
Energy Metabolism of the Heart in Catecholamine-Induced Myocardial Injury....Pages 23-43
The Permissive Role of Catecholamines in the Pathogenesis of Hamster Cardiomyopathy....Pages 45-53
Adaptive and Pathological Alterations in Experimental Cardiac Hypertrophy....Pages 55-77
Reflections on What Makes the Heart Grow....Pages 79-85
Force-Velocity-Length Relationship during Cardiac Hypertrophy....Pages 87-95
Hemodynamics, Regional Myocardial Blood Flow, and Sarcoplasmic Reticulum Calcium Uptake in Right Ventricular Hypertrophy and Failure....Pages 97-105
Myocardial Energy Metabolism of Congestive and Hypertrophic Cardiomyopathy in Man....Pages 107-113
Effects of Cardiac Work and Leucine on Protein Turnover....Pages 115-125
The Rate of Cardiac Structural Protein Synthesis in Perfused Heart....Pages 127-135
DNA Synthesis and Mitotic Activity in Adult Atrial Cardiocytes in Culture....Pages 137-145
DNA Synthesis in Atrial Myocytes of Rats with Aortic Stenosis....Pages 147-162
DNA Synthetic Activity of Right and Left Ventricular Biopsy Specimens in Patients with Cardiomyopathy....Pages 163-170
Comparative Changes in the 32 P Labeling of Adenine and Uracil Nucleotides in the Hypertrophying Rat Heart....Pages 171-181
Increased Synthesis of the Phosphorylated Form of the Myosin Light Chains in Cardiac Hypertrophy in the Rat....Pages 183-188
Reconstitution of Heavy Chain and Light Chain 1 in Cardiac Subfragment-1 from Hyperthyroid and Euthyroid Rabbit Hearts....Pages 189-193
Mechanisms of Degradation of Myofibrillar and Nonmyofibrillar Protein in Heart....Pages 195-199
Vasoactive Peptides and Regulation of Hemodynamics in Different Functional States of the Organism....Pages 201-214
Pathogenesis of Immune-Mediated Carditis in Monkeys....Pages 215-226
Immunologic Studies in Infective Endocarditis....Pages 227-232
Front Matter....Pages 1-1
Adaptation of the Organism during Long-Lasting Survival with a Total Artificial Heart....Pages 233-246
A Possible Mechanism of Adriamycin Cardiotoxicity....Pages 247-253
Effects of Propranolol and Hydrocortisone Pretreatment on Radiation-Induced Myocardial Injury in Rats....Pages 255-262
Inhibition of Vitamin D 3 -Induced Vascular Calcification by Carbocromen....Pages 263-267
Front Matter....Pages 269-269
Mitochondrial Function in Normal and Hypoxic States of the Myocardium....Pages 271-285
Cardiac Synthesis and Degradation of Pyridine Nucleotides and the Level of Energy-Rich Phosphates Influenced by Various Precursors....Pages 287-308
Effect of Exogenous Amino Acids on the Contractility and Nitrogenous Metabolism of Anoxic Heart....Pages 309-318
Regulation of Cardiac Contractility and Glycolysis by Cyclic Nucleotides during Hypoxia....Pages 319-325
Hypoxia, Calcium, and Contracture as Mediators of Myocardial Enzyme Release....Pages 327-331
Cyclic AMP and Early Contractile Failure....Pages 333-338
Release of Purine Nucleosides and Oxypurines from the Isolated Perfused Rat Heart....Pages 339-345
Pathophysiology of Irreversible Ischemic Injury....Pages 347-361
Acid Hydrolases in the Initiation of Ischemic Myocardial Necrosis....Pages 363-369
Release of Prostacyclin into the Coronary Venous Blood in Patients with Coronary Arterial Disease....Pages 371-378
The Effects of Systole on Left Ventricular Blood Flow....Pages 379-393
Prolonged Depletion of ATP Because of Delayed Repletion of the Adenine Nucleotide Pool following Reversible Myocardial Ischemic Injury in Dogs....Pages 395-407
Cytochrome Oxidase Activity of Mitochondria from Ischemic and Reperfused Myocardium....Pages 409-418
The Effect of Experimentally Induced Myocardial Ischemia on the Norepinephrine Metabolism of the Dog Heart....Pages 419-425
Reperfusion Injury....Pages 427-439
Ultrastructural, Functional, and Metabolic Correlates in the Ischemic Rat Heart....Pages 441-448
Front Matter....Pages 269-269
Detection of Intracellular Anoxia and Its Relationship to Onset of Hemodynamic Dysfunction and ST-Segment Elevation in the Intact Dog Heart....Pages 449-456
The Relationship between Glucose Utilization during Ischemia and Ventricular Fibrillation during Early Reperfusion....Pages 457-464
Correlation among Water Content, Left Ventricular Function, Coronary Blood Flow, and Myocardial Metabolism after Hypothermic Ischemic Cardiac Arrest....Pages 465-471
Serial Changes in Cytosolic, Mitochondrial, and Lysosomal Enzymes and Cardiac Myosin Light Chain II in Plasma following Coronary Ligation in Conscious Closed-Chest Dogs....Pages 473-478
Myosin Light Chain Phosphorylation during Regional Myocardial Ischemia....Pages 479-487
Myocardial Infarct Size from Serum Cardiac Myosin Light Chain....Pages 489-495
Biopsy Assessment of Preservation during Open-Heart Surgery with Cold Cardioplegic Arrest....Pages 497-504
Calcium Antagonistic Activity and Myocardial Ischemic Protection by Both Stereoisomers of Verapamil....Pages 505-512
The Effects of β Blockade and Partial Agonist Activity during Myocardial Ischemia....Pages 513-520
Cyclic Nucleotides and Changes in Protein Kinase Activity Ratio in the Ischemic and Nonischemic Myocardium....Pages 521-530
Myocardial Biosynthesis of Prostaglandins with Special Consideration of Prostacyclin and the Influence of Dipyridamole and Propranolol....Pages 531-537
Influence of Cardiovascular Drugs on Platelet Aggregation....Pages 539-547
Effects of L-Carnitine on Tissue Levels of Free Fatty Acid, Acyl CoA, and Acylcarnitine in Ischemic Heart....Pages 549-557
Effect of Coenzyme Q 10 on Hypertrophied Ischemic Myocardium during Aortic Cross Clamping for 2 hr, from the Aspect of Energy Metabolism....Pages 559-566
Preservation of Oxidative Phosphorylation by Lidocaine in Ischemic and Reperfused Myocardium....Pages 567-573
On the Mechanism of Action of the Antianginal Drug Nonachlazine on Ischemic Myocardium....Pages 575-587
Studies on Slow Cardiac Action Potentials Occurring in Potassium-Rich Media as a Simulation of the Early Phase of Myocardial Infarction....Pages 589-594
Antiischemic Effects of Molsidomine in an Experimental Model of Coronary Artery Stenosis....Pages 595-604
Effect of Molsidomine on Spontaneous Ventricular Fibrillation following Myocardial Ischemia and Reperfusion in the Dog....Pages 605-613
Back Matter....Pages 615-649