Advances in Membrane Biochemistry and Bioenergetics

Front Matter....Pages i-xiii
Front Matter....Pages 1-1
My Teachers and I....Pages 3-12
Reconstitution as a Research Programme: T. E. King 1956 – 1986....Pages 13-20
Front Matter....Pages 21-21
Introduction....Pages 23-24
Respiratory Chain Systems in Theory and Practice....Pages 25-52
Front Matter....Pages 53-53
Introductory Remarks....Pages 55-56
Flavoproteins; Correlation of Structure and Function....Pages 57-60
Mitochondrial Electron Transport: The Random Collision Model....Pages 61-74
Lateral Diffusion as a Rate-Limiting Step in Mitochondrial Electron Transport....Pages 75-85
The Pool Function of Ubiquinone in the Mitochondrial Respiratory Chain: Role of Lateral Diffusion....Pages 87-105
Effects of Long Chain Alkyl Compounds on Submitochondrial Particles: Mechanistic Differences between Nadh and Succinate Oxidases....Pages 107-114
Purification and Properties of the Rotenone — Insensitive NADH: Q 6 Oxidoreductase from Saccharomyces Cerevisiae ....Pages 115-119
An Ubiquinone-Binding Protein, A Constituent of Iron-Sulfur Fragment Isolated from Mitochondrial NADH-Ubiquinone Reductase (Complex I)....Pages 121-128
Construction of Yeast Mutants of QH 2 : Cytochrome C Oxidoreductase: Requirement of the 11, 14 and 17 kDa Subunits, but not the 40 kDa Subunit, for Enzymatic Activity....Pages 129-140
Electron Transfer and Spectral Changes in Cytochrome b Studied in Mitochondria from Coenzyme Q-Deficient Mutants of the Yeast Saccharomyces Cerevisiae Reconstituted with Coenzyme Q Analogues....Pages 141-153
Structural and Functional Features of the Eleven Constituent Proteins of the Mammalian Ubiquinol: Cytochrome c Reductase....Pages 155-165
A Mitochondrial Protein Essential for Interaction Between Cytochromes c 1 and c : The Hinge Protein....Pages 167-178
A Function of the Hinge Protein c 1 - c ....Pages 179-184
The Thiopropionyl Derivatives of Cytochrome C ....Pages 185-192
Monoclonal Antibodies of Mammalian Cytochrome Oxidase and its Protein Subunits....Pages 193-202
Biochemical Characterization of Boar Sperm Cytochrome Oxidase....Pages 203-217
Front Matter....Pages 53-53
Molecular Events in Cytochrome C Oxidase....Pages 219-225
The Cyanide-Resistant Oxidase in Higher Plant Mitochondria....Pages 227-233
Front Matter....Pages 235-235
Comparative Studies on the Nadh-Q Oxidoreductase Segment of the Bacterial Respiratory Chain....Pages 237-248
Pathways of Electron Transfer in Desulfovibrio ....Pages 249-258
Studies on a Novel Flavodoxin from the Respiratory Mutant TZN-200 from Azotobacter Vinelandii ....Pages 259-265
Electron Transfer Components of Manganese Oxidizing Bacteria....Pages 267-272
Biochemical and Genetic Approaches to Elucidating the Mechanism of Respiration and Energy Transduction in Paracoccus Denitrificans ....Pages 273-284
Reconstitution of Function in Fatty-Acid Inactivated Photosystem 2....Pages 285-290
Electron Transport in The Cytochrome B 6 F Complex....Pages 291-297
Front Matter....Pages 299-299
pH-Dependence of The Maximal Velocity of Cytochrome c Oxidase: Relation to Proton Translocation and Respiratory Control....Pages 301-309
Control of Proteoliposomal Cytochrome Oxidase: Normal and Inverted Orientations....Pages 311-321
Cytochrome C Peroxidase Activity of Cytochrome Oxidase and its Coupling to Proton Pumping....Pages 323-332
Characteristics of the Protonmotive Activity of the Cytochrome Chain of Mitochondria....Pages 333-345
Dependence of the 3-OH-Butyrate Dehydrogenase and Cytochrome c Oxidase Reactions on Intramitchondrial pH....Pages 347-356
Role of Coupling Factor B in the F o Proton Channel....Pages 357-362
ATP Synthesis and Ion Gradients in the Methanogenic Bacteria....Pages 363-387
Energy Transfer in Solute Carrier Transport....Pages 389-399
Interaction of Quinine with Mitochondrial K + Transport Mechanisms....Pages 401-408
Outer Membrane Lysis Increases Accessibility of Cationic Drugs to the Inner Mitochondrial Membrane....Pages 409-416
Front Matter....Pages 417-417
Optical and X-Ray Techniques in the Study of Rapid Ligand Binding: A Ligand „Docking“ Site in the Reaction of Mb and Co At 40 K....Pages 419-428
Front Matter....Pages 417-417
X-Ray Absorption Studies of Oriented Cytochrome Oxidase....Pages 429-438
Newly Developed Time-Resolved EPR Techniques for the Study of Cytochrome C Oxidase....Pages 439-447
EPR and Electron Spin Echo Studies of Iron-Sulfur Clusters S-1 And S-2 in Bovine Heart Succinate Dehydrogenase....Pages 449-458
New Avenues in Electron Microscopy of Transmembranous Biomolecular Assemblies....Pages 459-467
Structural Influences on the Electrochemistry of Ubiquinone....Pages 469-478
Front Matter....Pages 479-479
Enzymatic Synthesis of Acetono-CoA, A Competitive Inhibitor of Acetyl-CoA with Citrate Synthase....Pages 481-485
Purification and Properties of Two Isoenzymes of Tench Liver Arginase....Pages 487-496
Enzymes at Oil-Water Interfaces and in Organic Solvents....Pages 497-505
Conformational Changes at the Active Site of D-Glyceraldehyde-3-Phosphate Dehydrogenase During Unfolding in Guanidine Solution....Pages 507-515
Acute Stimulation by Peptide Hormones of Mitochondrial Steroid Hormone Synthesis: Production of a Similiar Protein in Three Steroidogenic Tissues....Pages 517-525
Interaction of Steroid Substrates with Cytochrome P-450 C21 -Proteoliposomes....Pages 527-533
Regulation of Cholesterol 7 α -Hydroxylase....Pages 535-539
Front Matter....Pages 441-441
An Overview of Biochemical and Clinical Research on Coenzyme Q with Emphasis on Cardiomyopathy and Muscle Dystrophy....Pages 543-551
Membrane Damage Provoked by Lipid Peroxides....Pages 553-560
Oxidation-Reduction Associated with Inhaled NO 2 Absorption....Pages 561-567
The Reconstitution of Biologically Active Glycoproteins into Large Liposomes: Use as a Delivery Vehicle to Animal Cells....Pages 569-586
Back Matter....Pages 587-603