Advances in Electrocardiology 2004: Proceedings of the 31th International Congress on Electrocardiology (Advances in Electrocardiography)

CONTENTS......Page 10
Preface......Page 8
1 Long QT Syndrome......Page 34
Introduction......Page 36
My First Patient......Page 37
Looking for Answers......Page 38
An American Partnership......Page 40
Impact......Page 41
Molecular Genetics......Page 42
Findings from the Registry......Page 43
References......Page 44
2 Atrial Fibrillation......Page 52
Clinical Consequences of Atrial Remodeling......Page 54
Different Models, Different Ion Channel Remodeling......Page 55
Reversed Remodeling and Different Types of Postcardioversion Recurrences......Page 56
Long-Term Efficacy of Antiarrhythmic Drug Therapy and its Influence to the Prognosis in Patients with Paroxysmal Atrial Fibrillation K. Okumura......Page 58
1. Introduction......Page 59
2. Myocardial Sleeve of PVs......Page 60
3. Electrical Properties of PV Myocardial Sleeves......Page 61
4.1. Ryanodine-induced Pacemaker Shifi in Rabbit Atrial Preparations......Page 62
4.2. Pacing-induced Spontaneous Activity in PVs Afler Treatment with Ryanodine......Page 63
4.3. Role of Intracellular Ca2+ Dynamics......Page 64
4.4. Implication for the Genesis of AF......Page 65
References......Page 66
1. Introduction......Page 67
2.2. Study Protocol......Page 68
2.5. Statistical Analysis......Page 69
3.3. Adverse Effects......Page 70
4. Discussion......Page 71
4.1. Electrophysiology of Bepridil and Aprindine......Page 72
4.3. Limitation......Page 73
References......Page 74
1. Background......Page 75
3.3. Development into Chronic AF......Page 76
3.4. Cox Proportional Hazard Model......Page 77
5. Conclusions......Page 78
References......Page 79
3 Basic Electrophysiology......Page 80
Mechanisms of Ventricular Fibrillation: Role of Inward Rectifyer Channels J. Jalife......Page 82
Introduction......Page 83
Results and Discussion......Page 84
Running Title......Page 85
References......Page 86
1. Introduction......Page 87
3. Results......Page 88
4. Conclusion......Page 89
Methods and Results:......Page 90
Losartan Decreases the Arrhythmogenic Activity of Pulmonary Vein Cardiomyocyte Y.-C. Chen, Y.-J. Chen, S.-A. Chen and C.-I. Lin......Page 91
Methods......Page 92
Major Findings......Page 93
Renin-angiotensin System......Page 94
References......Page 95
Amiodarone not only Reverses Electrical Remodeling but Suppresses Matrix Metalloproteinases 2 Activity in Canine Pacing-Induced Persistent Atrial Fibrillation Model K. Ashikaga, T. Kobayashi, M. Kimura, S. Owada, T. Higuma, S. Sasaki, A. Iwasa, K. Furu......Page 96
1. Introduction......Page 97
3.2. Changes in AERPs at BB and LA Sites......Page 98
4. Summary......Page 100
5. Conclusions......Page 101
1. Materials and Methods......Page 102
2.1. Incidence of Arrhythmias in LA-PV Preparations......Page 103
2.2. APs and Transient Outward Currents in Ventricular Myocytes of Xin-gene KO Versus Wild-type Mice......Page 104
References......Page 105
Heterogeneous Distribution of the Muscarinic K+ Channels in Guinea-pig Atria Y. Yasuda, H. Toda, W.-G. Ding, F. Toyoda, M. Itoh, M. Horie and H. Matsuura......Page 106
Electrophysiology of Single Cardiomyocytes Isolated from Left Atrium and Pulmonary Veins of Myopathic versus Heathly Hamsters Y.-X. Loh, Y.-C. Chen and C.4. Lin......Page 107
1. Introduction......Page 108
2. Method......Page 109
Modeling the Ca2+ Gate of a Hemichannel......Page 110
4. Discussion......Page 111
References......Page 112
Role of ERK-Mediated Suppression of Gap Junction Permeability in Cardioprotection Afforded by MITO-KATP Channel Activation Y. Ichikawa, T. Miura, T. Miki, J. Sakamoto, Y. Nakamura, T. Yano and K. Shimamoto......Page 114
1. Introduction......Page 115
3. Results......Page 116
References......Page 118
Results and Discussion......Page 120
Reference......Page 122
1. Introduction......Page 125
3.1. Changes of Intracellular Calcium by PAF Application......Page 126
3.2. Effects of PAF on the L-type Calcium Channel Current......Page 127
4. Discussion......Page 128
References......Page 129
1. Introduction......Page 130
2.2. RNA Extraction, DNA Microarray and Northern Blot Analysis......Page 131
3.2. Northern Blot Analysis......Page 132
References......Page 133
1. Introduction......Page 136
2. Results......Page 137
3. Conclusion......Page 139
References......Page 140
Electrophysiological Effects of Palmitate on Rabbit Pulmonary Vein Myocardial Cells S. Higa, Y.-C. Chen, J. Wei, M. Shimabukuro and C.-I. Lin......Page 141
Rapid Atrial Pacing Upregulates Synthesis of Asymmetric Dimethylarginine in Canine AF Model T. Kobayashi, K. Ashikaga, M. Kimura, S. Owuda, T. Higuma, S. Sasaki, A. Iwasa, T. Osunai, S. Motomura and K. Okumura......Page 142
Combined Effects of Nifekalant and Lidocaine on Spiral-Type Reentrant Ventricular Arrhythmias in Rabbit Hearts M. Amino, K. Yoshioka. K. Usui, Y. Deguchi, T. Tanabe, M. Yamazaki, H. Nakagawa, K. Yasui, H. Honjyo, K. Kamiya and I. Kodama......Page 143
Regional Abnormality of Restitution Properties Cause Electrical Alternans and Arrhythmia in Chronic Myocardial Infarction Y. Hosoya, K. Yuuki, I. Kubota and M. Yumaki......Page 144
Purpose......Page 145
Analysis of Virtual Electrode Polarization Induced Break Excitation and Capture Mechanisms of Excitation Propagation by Electrical Point Stimulus T. Arafune, Y. Takata, S. Nashimoto, T. Yamaguchi, E. Kobayashi, I. Sakuma, N. Shibata, H. Nakagawa, M. Yamazaki, H. Honjo, K. Kamiya and I. Kodama......Page 146
1. Introduction......Page 147
2. Methods......Page 148
3. Results......Page 149
4. Discussion......Page 150
References......Page 151
2. Methods......Page 152
3.1. Effects of Regional Epicardial Cooling of the RVOT and Additional VNS on Surface ECG and MAP......Page 153
3.3. Venhicular Vulnerability......Page 154
References......Page 155
Long-Term Treatment with Glibenclamide Increases Susceptibility of Streptozotocin-Induced Diabetic Rat Heart to Reperfusion-Induced Ventricular Tachycardia N. Takahashi, T. Ooie, M. Nakagawa and T. Saikawa......Page 157
4 Genetics of Arrhythmias......Page 158
1. Introduction......Page 160
3.1. Animal Characteristics......Page 161
3.3. Configuration of Electrocardiograms in Complete A VB Mouse......Page 162
References......Page 163
1. Introduction......Page 164
5. Result......Page 165
References......Page 166
Conclusions;......Page 167
Conclusions;......Page 168
Conclusions......Page 169
Clinical Relevance of Pilsicainide Challenge Test for Risk Stratification of Sudden Cardiac Death in Patients with Brugada Type ECG S. Sasaki, A. Iwasa, T. Higuma, S. Owada and K. Okumura......Page 170
Complete RBBB Pattern in ECGs in Patients with Brugada Syndrome Associated with a Higher Incidence of Ventricular Fibrillation Events N. Tsuboi, I. Kodama, Y. Yoshida, K. Tajima, H. Hirayama, T. Itoh, J. Toyama, K. Yamada, T. Yamada and Y. Murakami......Page 171
Objective:......Page 172
5 Computer Simulation......Page 174
1. Introduction......Page 176
3.1 Spatial Distribution of AV,,, and Its Dependence on Shock Strength......Page 177
3.3 Shock-induced AV, Maps in a Sheet......Page 178
4. Discussion......Page 179
References......Page 180
1 Background......Page 181
3 Results and Conclusions......Page 182
References......Page 184
Computer Simulations on High Frequency Components of ECG Due to Micro-Necroses Y. Okamoto, N. Zenda, M. Kasama, H. Shimojima and T. Tsutsumi......Page 185
On the Genesis of the Injury Potentials Y. Okamoto, M. Kondoh and S. Mashima......Page 186
1. Introduction......Page 187
3. Results and Discussion......Page 188
References......Page 190
2. Method and Material......Page 191
3. Results......Page 192
4. Discussion and Conclusions......Page 194
References......Page 195
6 Sudden Cardiac Death......Page 196
Electrocardiographic Predictors of Cardiac Events in MADIT I1 Patients W. Zareba......Page 198
Quantification of Heart Rate Turbulence......Page 199
Patients......Page 200
Disease......Page 201
Conclusions......Page 202
References......Page 205
1. Introduction......Page 207
2.1. Subjects......Page 208
2.4. Statistical Analysis......Page 209
3.2. Test of Low HRV......Page 210
3.3. Survival Analysis......Page 211
4. Discussion......Page 212
References......Page 214
Risk Stratification for Sudden Cardiach Death Using Microvolt T-Wave Alternans in Postmyocardial Infarction Patients T. Ikeda, K. Sugi and H. Yoshino......Page 215
Measurement of Microvolt TWA......Page 216
Follow-up and End Points......Page 217
Outcome of Prognostic Valuables......Page 218
Discussion......Page 219
References......Page 220
Clinical Application of BRS (Baroreflex Sensitivity) for Risk Stratification of Sudden Cardiac Death and CHF R. Nohara......Page 225
BRS and Survival:......Page 226
References......Page 229
Corrected QT Dispersion is the Predictor in Coronary Microvascular Ischemia T. Ohta, S. Kodama, N. Morito, E. Yahiro, H. Mihara, K. Miyoshi, Y. Yamanouchi and H. Urata......Page 232
Conclusions:......Page 233
7 New Frontier in Basic Cardiac Electrophysiology......Page 234
1.1. Introduction......Page 236
1.3. Diagnostic Criteria......Page 237
1.4. Genetic Basis......Page 239
1.5. Cellular and Ionic Basis......Page 240
1.6. Risk Stratification......Page 243
1.7. Approach to Therapy......Page 244
References......Page 246
Methods and Material......Page 252
Ca” Release from Endoplasmic Reticulum......Page 253
VOCCs......Page 254
Na+/Ca2' Exchanger Ca2+ Extrusion Systems......Page 255
Ca2+ Entry through DHP Receptros......Page 256
Activities of Na'm (pump) ATPase in mES Cells and Derived Cardiomyocytes......Page 257
Molecular Study in Na'm ATPase and Na+/Caz' Exchangers......Page 258
# 3 ; Conclusion......Page 259
References......Page 260
Introduction......Page 263
Analysis of mRNA Expression of L-type and T-type Ca2+ Channels......Page 264
L-type CaZf channel currents......Page 265
Statistics......Page 266
mRNA expressions......Page 267
L-type Ca2+ channel current......Page 268
T-type Ca2+ channel current......Page 269
8 Ion Channels......Page 272
2. Methods......Page 275
3.5. Shifi from Flutter to Fibrillation......Page 276
4. Discussion......Page 277
References......Page 278
1. Introduction......Page 279
2. Methods......Page 280
3. Results......Page 281
References......Page 282
ATP-Sensitive K+ Channel is not Involved in the Extracellular K+ Accumulation in Ischemic Mouse Heart T. Sato, T. Saito, T. Miki, S. Seino and H. Nakaya......Page 283
Sealing of Electrically Ruptured Pores by LA3+ and Polyethyleneglycol in Rabbit Ventricular Cell Membrane R. Ochi, Y. Song and L. Fan......Page 284
1. Materials and Methods......Page 285
2.2. The Negative Znotropy of High Concentration of Insulin......Page 286
2.3. Egects of Insulin and IGF-1 on Transmembrane Calcium Injlm......Page 287
References......Page 288
1. Introduction......Page 290
3.1. ATl-receptor Stimulation Increased IKs Current......Page 291
4. Discussion......Page 292
References......Page 293
Molecular and Functional Properties of T-Type Ca2+ Channel in Mouse Embryonic Hearts N. Niwa, K. Yasui, T. Opthof; H. Takemura, A. Shimizu, M. Horiba, J.-K. Lee, H. Honjo, K. Kamiya and I. Kodama......Page 294
Effects of Eicosapentaenoic Acid on the Electrophysiological Characteristics of Rabbit Left Atrial-Pulmonary Vein Cardiomyocytes I.-J. Chen, Y.-C. Chen, J. Wei and C.4. Lin......Page 295
Two Modes of Polyamine Block Regulating the Cardiac K+ Current IK1 as Revealed by a Study of the Kir2.1 Channel K. Ishihara......Page 296
1. Introduction......Page 297
3. Results......Page 298
4. Discussion......Page 299
References......Page 300
Relationship between KChIP2 and Transient Outward Current of Developing Rat Heart T. Kobayashi, Y. Yamada, M. Nagashima, M. Fukao, K. Kameda, S. Seki, M. Tsutsuura, Y. Ito, I. Sakuma, H. Hamada, T. Abe and N. Tohse......Page 301
Deprivation of Membrane Cholesterol Depresses Camp-Dependent Enhancement of L-Type CA Current in Rabbit Ventricular Myocytes H. Tsujikawa, H. Masumiya, Y. Song, C. Jin and R. Ochi......Page 302
Potentiation of IKS Potassium Current in Guinea-pig Ventricular Myocytes by Sphingosine- 1 -Phosphate H. Toda, W.-G. Ding, F. Toyoda, Y. Yasuda, M. Ito, M. Horie and H. Matsuura......Page 303
1. Introduction......Page 304
2. Results & Discussion......Page 305
References......Page 306
Introduction......Page 307
Results......Page 308
Discussion......Page 309
References......Page 310
1. Introduction......Page 311
3.1. Acute Inhibitory Effect of Amiodarone on IK,......Page 312
Acknowledgments......Page 313
References......Page 314
CONCLUSIONS:......Page 315
Introduction......Page 316
Case 1; 9 year-old female......Page 317
Case 2; 9 year-old female......Page 318
References......Page 319
Phenotypical Overlapping of Sick Sinus find Brugada Syndromes in a Family with a Novel SCN5A Mutation F. Yanagisawa, Y. Higashi, H. Shimojima, T. Tsutsumi, Y. Takeyama, N. Zenda, T. Makiyama and M. Horie......Page 320
1. Background......Page 321
2.4. Confocal Laser Microscopy......Page 322
3. Results......Page 323
4. Summary......Page 324
Acknowledgments......Page 325
Co-Cultured Skeletal Myocyte and Cardiomyocyte Cell-Sheets could not Establish Electrical Communication, but Caused Fibrillating Activity in Cardiomyocyte S. Miyoshi, Y. Itabashi, K. Fukuda, K. Tanimoto, T. Shimizu, Y. Hagiwara, A. Furuta, T. Tanaka, N.Nishiyama, T. Okano, H. Mitamura and S. Ogawa......Page 274
9 Genetic Basis for Cardiac Arrhythmias......Page 326
DNA Microarrays and Arrhythmias D. G. Escande......Page 328
Introduction......Page 330
Long QT Interval Syndromes......Page 331
Brugada Syndrome......Page 333
Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)......Page 334
Andersen Syndrome......Page 335
Clinical Implications of Identification of Genetic Defects in These Disorders......Page 336
References......Page 340
Allelic Variants in Cardiac Ion Channel Genes in Patients with Drug-Induced Long QT Syndrome H. Kanki......Page 344
2. Congenital LQTS......Page 345
3. Brugada Syndrome......Page 347
4. Acquired Long QT Syndrome......Page 349
References......Page 351
10 Clinical Arrhythmias......Page 352
1. Introduction......Page 354
3. Results......Page 355
Effects of Bepridil on Ventricular Response During AF......Page 356
References......Page 357
Background:......Page 359
Materials and Methods......Page 360
References......Page 361
Bulgarian General Practitioners’ Knowledge about the Atrial Fibrillation Management B. Georgiev, N. Gotcheva and I. Tomov......Page 363
Results......Page 364
Discussion......Page 365
References......Page 366
Background:......Page 368
The Differences in the Bulgarian General Practitioners’ and Cardiologists’ Approach to the Supraventricular Tachycardias Management B. Georgiev, N. Gotcheva and I. Tomov......Page 369
Results......Page 370
Discussions......Page 371
Acknowledgement......Page 372
Efficacy of Nifekalant Hydrochloride on the Management of Life-Threatening Ventricular Tachyarrhythmias in Patients with Non-Ischemic Cardiomyopathy T. Washizuka, M. Chinushi, H. Furushima, H. Watanabe and Y. Aizawa......Page 373
4. Conclusions......Page 374
6. Figures......Page 375
References......Page 376
Purpose......Page 377
Results......Page 378
Conclusion......Page 379
References......Page 380
Conclusions:......Page 381
Conclusion:......Page 382
2. Introduction......Page 383
3.1. Figure 1......Page 384
3.2. Figure 2......Page 385
References......Page 386
Methods......Page 387
Results......Page 389
References......Page 390
1. Introduction......Page 391
3.1. Change of QT and RR Intervals......Page 392
4. Discussion......Page 393
References......Page 394
Critical Roles of Pilsicainide at Termination of Atrial Flutter Studied by Noncontact 3D Mapping in the Canine Incision Model K. Uno, T. Iwa, I. Kato, Y. Suzuki, M. Fukuta, Y. Wakita, T. It0 and K. Shimamoto......Page 395
3. Results......Page 396
Discussion......Page 397
References......Page 398
Introduction......Page 399
Methods......Page 400
Statistical Methods......Page 401
Discussion......Page 402
Conclusions......Page 403
References......Page 407
1. Background......Page 409
3. Material and Methods......Page 410
4. Results......Page 411
References......Page 412
Introduction......Page 413
Methods......Page 414
Results......Page 415
Conclusion......Page 416
References......Page 417
11 Clinical Electrophysiology......Page 418
Distinctive Electrophysiological Properties of Pulmonary Veins in Patients with Paroxysmal Atrial Fibrillation against Isoproterenol K. Motoki, H. Takui, H. Yabushita, K. Ikoma, R. Yasuoka, T. Hayashi and K. Ishikawa......Page 420
Introduction......Page 421
Results......Page 422
Conclusion......Page 424
References......Page 425
Introduction......Page 426
Analysis of Clinical Outcomes and Follow-up......Page 427
Efficacy of PV Isolation on Paroxysmal and Persistent AF......Page 428
Conclusion......Page 429
References......Page 430
Clinical and Electrocardiographical Predictors of Immediate Recurrence of Atrial Fibrillation after External Cardioversion B. Gorenek, G. Kudaiberdieva, Y. Cavusoglu, 0. Goktekin, A. Birdane, N. Ata, A. Unalir and B. Timuralp......Page 431
Relation Between Transverse Conduction Capability and the Anatomy of the Crista Terminalis in Patients with and without Atrial Flutter Y. Okumura, I. Watanabe, K. Ohkubo, H. Sugimura, K. Hashimoto, Y. Takagi, T. Nakai, S. Saito, Y. Ozawa and K. Matsumot......Page 432
Pulmonary Vein Potentials were Completely Organized by Pilsicainide Administration just before Termination of Atrial Fibrillation A. Iwasa, S. Ohwada, S. Sasaki and K. Okumura......Page 433
Conclusions:......Page 434
Electropharmacologic Evaluation of Quinidine in the Brugada Syndrome Y. Mizusawa, H. Sakurada, T. Sakai, H. Yamaguchi, J.-C. Oh, H. Okazaki, T. Tejima, M. Nishizaki and M. Hiraoka......Page 435
1. Introduction......Page 436
Recruitment of Patients......Page 437
Other Characteristics......Page 438
Conclusion......Page 439
1.1. Background......Page 441
1) Actual cases......Page 442
1.5. Conclusion......Page 444
References......Page 452
1. Background......Page 454
3.1. The Prognosis of Sudden Death Survivors......Page 455
3.3. Sudden Death Case......Page 456
4. Discussion......Page 458
5. Conclusion......Page 461
References......Page 462
Conclusion......Page 463
2. Methods......Page 464
4. Conclusion......Page 465
References......Page 467
A Novel Radiofrequency Catheter Ablation Technique for Creation of Cavotricuspid Isthmus Block in Isthmus-Dependent Atrial Flutter M. Maruyama, Y. Kobayashi, Y.-K. Iwasaki, Y. Miyauchi, S. Miyamoto, T. Tadera, T. Ino, H. Atarashi, T. Katoh and T. Takano......Page 468
Frequent Association of Atrial Fibrillation does not Mean Increased Atrial Vulnerability in WPW Syndrome: Presence of “Patients Referral Bias”? K. Kuga, M. Endoh, B. Niho, A. Suzuki, M. Kanemoto. M. Enomoto, K. Yoshida and I. Yamaguchi......Page 469
Case Report......Page 470
Discussion......Page 472
References......Page 473
Optimal Temperature and Acute Effect on Sinus Node of Ablation at Junction between Superior Vena Cava and Right Atrium; Electrophysiological and Histological Evaluation Using our Thermal Balloon Catheter K. Tanaka, H. Sohara, S. Satake, Y. Watanabe and......Page 475
Results......Page 476
Conclusion......Page 477
References......Page 478
Latent Mahaim Fiber Conducted during only in Atrioventricular Reentrant Tachycardia A. Moriyama, Y. Enjoji, H. Itakura, K. Kumagai, T. Sakai, T. Nakae, N. Tezuka, T. Sakata, M. Nor0 and K. Sugi......Page 480
A Simple Criterion of “V-H-A Pattern by Ventricular Extrastimulus” for the Diagnosis of Atrioventricular Nodal Reentrant Tachycardia S. Owada, T. Higuma, S. Sasaki, M. Kimura, T. Kobayashi, K. Ashikaga and K. Okumura......Page 481
Specific Findings of the Standard 12-Lead Electrocardiogram in Patients with Transient Left Ventricular Apical Ballooning: Comparison with Anterior AM1 R. Ogura, Y. Hiasa, T. Takahashi, T. Tomokane, Y. Ohara, H. Miyajima, T. Ogata, N. Suzuki, K. Yuba, K. Kishi and R. Otani......Page 482
Septal Q Waves in V6 Lead Disappear during Narrow QRS Supraventricular Tachycardia: A New ECG Observation M. Noda, F. Suzuki, K. Motokawa and M. Isobe......Page 483
Causes of Exercise-Induced ST-Segment Elevation in Old Anterior Myocardial Infarction S. Taniai, Y. Koide, S. Yusu, K. Sakata, M. Yotsukura, T. Ikeda and H. Yoshino......Page 484
Electrocardiographic Characteristics of Idiopathic Ventricular Tachycarrhythmia Originating from the Right Ventricular Inflow Tract Y. Tanaka, Y. Yamauchi, A. Takahashi, K. Kumagai, Y. Yokoyama, K. Kurihara, A. Sato and K. Aonuma......Page 485
Morphological Evaluation of Idiopathic Left Ventricular Tachyarrhythmia from Anterior Aspects of Mitral Annulus Compared with those from Aortic Sinus Cusps K. Kumagai, A. Takahashi, Y. Yamauchi, Y. Yokoyama, K. Kurihara, Y. Tanaka. A. Satou and K. Aonuma......Page 486
Conclusions.......Page 487
Case reports......Page 488
References......Page 491
Case Report......Page 492
References......Page 493
2.1. Subjects......Page 495
3.2. Induction of Coronary Artery Spasm......Page 496
3.3. Case Presentation......Page 497
5. Conclusion......Page 498
Influence of Acute Vagal Activity in the Patients with Brugada Syndrome N. Yamawake, M. Nishizaki, T. Ogawa, S. Sugawara, H, Fujii, T. Ashikaga, M. Arita, H. Sakurada, M. Isobe and M. Hiraoka......Page 499
Background......Page 500
Conclusion......Page 501
References......Page 502
1. Introduction......Page 504
Statistics......Page 505
4. Discussion......Page 506
References......Page 507
Prevalence of Atrial Fibrillation Caused by Acute Atrial Dilation Decreased in Rat Diseased Heart H. Suzuki, H. Otake and Y. Maruyama......Page 509
Long Term Efficacy of PV Isolation for Penitent Atrial Fibrillation Patients K. Hashimoto, I. Watanabe, K. Kawauchi, Y. Okwnura, K. Ookubo, H. Sugimura, T. Nakai, S. Saito, Y. Ozawa and K. Matumoto......Page 510
P Wave Morphology of an Arrhythmogenic Focus with Paroxysmal Atrial Fibrillation Originating from SVC or Right Superior Pulmonary Vein K. Ohkubo, I. Watanabe, Y. Okumura, T. Yamada, H. Sugimura, T. Nakai, K. Hashimoto, S. Saito, Y. Ozawa and K. Matsumot......Page 511
Methods......Page 512
Patient Characteristics......Page 513
Discussion......Page 514
References......Page 515
Effects of Pulmonary Venous Isolation during Atrial Fibrillation: Frequency Domain Analysis of Electrograms Recorded by a Basket Catheter S. Sakurai, K. Uno, D. Nagahara, K. Tsuchihashi and K. Shimamoto......Page 516
1. Introduction......Page 517
3.1 QT Dispersion during Common Bile Duct Treatmant......Page 518
3.2 Autonomic Nervous Activity During Common Bile Duct Treatment......Page 519
Discussion......Page 520
References......Page 521
2. Methods......Page 522
3. Results......Page 523
References......Page 524
Introduction......Page 525
Materials and Methods......Page 526
Discussion......Page 527
References......Page 528
12 Body Surface Mapping......Page 530
1. Introduction......Page 532
3. Results......Page 533
References......Page 535
1. Introduction......Page 536
2. Material......Page 537
4. Results......Page 538
References......Page 539
Patients and Methods......Page 540
Results......Page 541
Discussion and Conclusions......Page 543
Acknowledgement......Page 544
1. Introduction......Page 545
2. Material and Methods......Page 546
3. Results......Page 547
References......Page 548
4th International Congress on Electrocardiology 20-23 September, 1977 Balatonfiired, Hungary......Page 550
8th Congress of the International Society of Electrocardiology. 1-4 September, 1981, Budapest, Hungary......Page 551
16th International Congress on Electrocardiology, 4-6 September, 1989, Budapest, Hungary......Page 552
References......Page 553
1.1 Nine Point Method (NPM)......Page 554
2.1 Comparing Laplacian Approximations of FPM, CNPM & NPMAnd Error Calculations......Page 555
2.3 Comparing Laplacian Approximations of Bi-polar & Tri-polar Electrodes And Error Calculations.......Page 556
References......Page 557
1 Introduction......Page 558
2 Methodology......Page 559
References......Page 561
1. Introduction......Page 562
3. Method......Page 563
4. Results......Page 564
References......Page 565
Patients and Methods......Page 566
Results......Page 567
Discussion and Conclusions......Page 569
Acknowledgement......Page 570
The SIT Integral in Detection of Healed Myocardial Infarction Assessed with Body Surface Potential Mapping P. Vesterinen, H. Hanninen, M. Karvonen, K. Lauerma, M. Holmstrom, M. Makijarvi, H. Vaananen, J. Nenonen and L. Toivonen......Page 571
2. Methods......Page 572
3. Results......Page 573
References......Page 574
The Effect of Percutaneous Coronary Artery Intervention on Body Surface Potential Maps M. Medvegy, E. Szucs, G. Simonyi, T. Bauemfeind, G. Duray, K. Szakolczai, R. G. Kiss, R. J. Bedros, R. A. Nadeau and I. Prkda......Page 575
Conclusions.......Page 576
1. Introduction......Page 577
3. Methods......Page 578
4. Results......Page 579
References......Page 580
Assessment of the Diastolic Function by Body Surface Potential Maps in Ischemic Heart Disease T. Bauemfeind, I. Prkda, E. Szucs, G. Duray, G. Simonyi, K. Szakolczai, R. G. Kiss, R. J. Bedros and M. Medvegy......Page 581
Simulation and Measurement of Single Component versus Three Component Cardiomagnetic Fields J. Haueisen, L. di Rienzo, C. M. Arturi, M. Liehr and M. Goering......Page 582
Non-Invasive Assessment of Atrial Wave Length by P Wave Signal Averaged Electrocardiography N. Makino, H. Maekawa, T. Shimonagata, N. Misaki, T. Yamada, M. Asai, H. Kioka, S. Tamaki, T. Matsumoto and M. Fukunami......Page 583
1. Introduction......Page 584
2. Patients and Methods......Page 585
3. Results......Page 586
4. Discussion......Page 587
References......Page 589
1. Background......Page 590
2. Methods......Page 591
4. Discussion......Page 592
References......Page 593
13 ECGNCG......Page 594
2. Objectives......Page 596
4.1. In Study 1......Page 597
5.2. In Study 2......Page 598
References......Page 599
1. Introduction......Page 600
3.2.1 Autoregressive moving average model......Page 601
3.2.3 Quantification of AIQP......Page 602
6. Conclusions......Page 603
References......Page 604
Results......Page 605
Conclusions......Page 606
Body Surface Potential Mapping to Identify Patients with Ejection Fraction Improvement after Biventricular Pacing N. Samesima, C. A. Pastore, N. Tobias, A. Pedrosa, L. F. Moreira, S. Nishioka, M. Martinelli F" and J. F. Ramires......Page 607
Material and Method......Page 608
Biventricular Pacemaker Implantation......Page 609
Results......Page 610
Discussion......Page 613
References......Page 615
1. Introduction......Page 618
4. Results and Discussion......Page 619
References......Page 621
Body Surface Potential Mapping Electro-Temporal Study of Resynchronization Patients with LBBB and Heart Failure: Comparison of Right and Left Ventricular Activation C. A. Pastore, N. Tobias, M. M. Filho, A. Pedrosa, S. Nishioka, R. A. Douglas, L. F. Moreira and J. F. Ramires......Page 623
1. Introduction......Page 624
2.1. Study Population......Page 627
2.2. Methods......Page 629
3. Results......Page 631
4. Discussion......Page 633
4.2. Study Limitations......Page 636
References......Page 637
1. Introduction......Page 641
2.2. Holter ECG Recordings and Data Analysis......Page 642
3. Results......Page 643
References......Page 644
2. Methods......Page 645
3. Results......Page 647
References......Page 648
Introduction......Page 650
Results......Page 651
References......Page 652
Patient Population......Page 654
ECG Measurements......Page 655
Exercise ECG Data......Page 656
Rate Adaptation of QT and QTp Intervals......Page 657
Discussion......Page 658
References......Page 659
Introduction......Page 660
Methods......Page 661
Results......Page 662
Minimum AFCL and Refractory Period......Page 663
Conclusions......Page 664
References......Page 668
1 Introduction......Page 669
3 Results......Page 670
References......Page 672
Electrocardiography Fails to Diagnose Left Ventricular Hypertrophy Accurately in Women H. Ochi, S. Miyata, A. Noda, M. Iwase, S. Kuroki, Y. Koike, R. Ito, H. Yamada and M. Yokota......Page 673
Results......Page 674
References......Page 675
2. Method and Experimental Material......Page 677
3. Results and Discussion......Page 679
References......Page 680
1.2 Methods......Page 681
1.3 Results......Page 682
1.3 Discussion......Page 684
References......Page 685
Conclusion:......Page 686
2. Methods......Page 687
3. Results......Page 688
References......Page 690
Conclusion:......Page 691
Conclusion:......Page 692
1. Introduction......Page 693
3. Results......Page 695
References......Page 696
1. Materials and Methods......Page 698
The former diagnostic criteria......Page 699
2.3. Diagnostic Accuracy of Computer Interpretations......Page 700
Conclusion......Page 702
1. Introduction......Page 703
2. The Derived 12-lead ECG......Page 704
3. A 12-lead ECG Telemonitor......Page 705
References......Page 706
1. Introduction......Page 708
2. Methods......Page 709
References......Page 711
1. Introduction......Page 712
3.2. High-frequency Spectral Analysis of SAECG......Page 713
4. Results......Page 714
Acknowledgments......Page 715
References......Page 716
Assessment of Signal-Averaged P-Wave as a Predictor of Postoperative Atrial Fibrillation after Coronary Artery Bypass Graft Surgery T. Nakai, Y. Kasamaki, T. Yamada, K. Okubo, K. Tokai, K. Hashimoto, A. Sezai, I. Watanabe, S. Saito and K. Matsumoto......Page 717
Different Manifestation of Premature Ventricular Contractions by their Origin S. Nakahara, K. Takayanagi, T. Nakata, K. Tanaka, I. Hisauti, T. Hayashi and S. Morooka......Page 718
Methods......Page 720
Discussion......Page 721
Conclusion......Page 722
References......Page 723
1.1. Autonomic Nervous Activity and Its Evaluation......Page 724
2.2. Analysis......Page 725
3.1. Diurnal Change of the Minimum and Maximum Y-values......Page 726
4. Discussion......Page 727
References......Page 728
Methods......Page 729
Results......Page 730
Discussion......Page 731
References......Page 732
1. Introduction......Page 733
2.3. R wave Detection......Page 734
3.1. Rpeak Detection Evaluation......Page 735
5. Conclusion......Page 736
References......Page 737
1. Introduction......Page 738
2.1. The Flow ofAnalysis Work......Page 739
2.2.1. Time Delay......Page 740
References......Page 741
1. Introduction......Page 742
3. Proposed Method......Page 743
4. Experiment......Page 744
References......Page 745
Method......Page 746
Discussion......Page 747
References......Page 749
14 Autonomic Nervous Activity......Page 750
Exaggeration of Morning Fluctuation of Autonomic Nervous Activity in the very Elderly Healthy Subjects H. Tasaki, T. Serita, C. Ueyama, K. Kitano, S. Set0 and K. Yano......Page 752
Methods......Page 753
Gender Diflerences in Isoproterenol-induced QT Interval Changes......Page 754
Effects of Isoproterenol on Ventricular Repolarization......Page 755
References......Page 756
1. Introduction......Page 758
4. Results......Page 759
References......Page 761
Introduction......Page 763
Study Protocol......Page 764
Discussion......Page 765
References......Page 766
15 Pacing......Page 768
Optimal AV Delay is not Preferred to Spontaneous AV Conduction in Patients with Pacemaker C. Suga, K. Matsumoto, R. Kato, T. Tosaka, T. Tamaki, T. Yamazaki and S. Nishimura......Page 770
1. Introduction......Page 771
2. Method......Page 772
References......Page 774
Ventricular Pacing Thresholds Following High-Energy Ventricular Defibrillation Shocks Y. Yamanouchi, S. Kodama, T. Ohta, N. Morito, E. Yahiro, K. Miyoshi and H. Urata......Page 776
Prevention of Atrial Fibrillation by Biatrial Pacing: The Outcome and the Electrophysiological Mechanism of Prevention Y. Enjoji, T. Sakata, M. Noro, T. Nakae, N. Tezuka, K. Kumagai, T. Sakai, H. Itakura, A. Moriyama and K. Sugi......Page 777
16 Pediatric ECG......Page 778
1. Introduction......Page 780
3. Results......Page 781
4. Discussion......Page 782
References......Page 783
1. Introduction......Page 785
3. Results......Page 786
4. Discussion......Page 787
References......Page 788
1. Introduction......Page 789
2. Methods......Page 790
3. Result......Page 791
4. Discussion......Page 792
References......Page 793
2 Objective......Page 794
3 Methods......Page 795
4 Results and Discussions......Page 796
5 Practical Conclusions......Page 798
References......Page 799
Drug Sensitivity and Antiarrhythmic Treatment in Children with Idiopathic Polymorphic Ventricular Tachycardia T. Yasuda, N. Kojima, D. Fukumi and M. Nagashima......Page 801
Efficacy of 12 Leads Holter Monitoring System in Brugada Syndrome - Multicenter Heart Screening Study in Japan - N. Surnitomo, M. Nagashima, H. Ushinohama, N. Konishi, S. Sato, S. Yasukochi, Y. Nakumura, N. Izumida, M. Yoshinaga, K. Karasawa, M. Ayusawa, H. Kato and K. Harada......Page 802
Discussion......Page 803
Conclusions......Page 804
References......Page 806
Model and Method......Page 807
Results and Discussion......Page 808
References......Page 810
1. Introduction......Page 811
2. Tissue Models and Simulation Mesh......Page 812
3. Simulation Results......Page 814
Acknowledgments......Page 815
Background......Page 816
Case Report......Page 817
Discussion......Page 818
References......Page 819
Chronic Angiotension II Receptor Blocker does not Alter Ventricular Defibrillation Thresholds Y. Yamanouchi, S. Kodama, T. Ohta, N. Morito, E. Yahiro, K. Miyoshi and H. Urata......Page 824
2. Objective......Page 825
3. Method......Page 826
4.3. Usability Test......Page 827
References......Page 828
2. Material......Page 829
3. Methods......Page 830
4. Results......Page 831
References......Page 832
2. Material and Methods......Page 834
3. Results......Page 835
4. Discussion......Page 836
Referenses......Page 837
17 Modeling of Cardiac Electrical Activity......Page 838
2. Modeling The T Wave......Page 840
2.2. T Wave Models......Page 841
3. Wilson’s Ventricular Gradient and the QRS-T Angle......Page 842
4. The Primary and the Secondary T Wave......Page 846
References......Page 847
Electrocardiographic Imaging (ECGI): Validation and Application in Humans Y. Rudy......Page 849
Whole Heart Model and ECG/MCG Inverse Problem Y. Okamoto......Page 850
1. Introduction......Page 851
2. Methods......Page 852
3.1. Electrical Activity in Acute Global Ischemia......Page 853
3.2. Ischemia-induced Changes in VGs......Page 854
3.3. Post-shock Activity......Page 855
4. Discussion......Page 856
References......Page 858
2 Methods......Page 860
4 Discussion......Page 862
References......Page 863
Analysis of QT Interval Prolongation by Simulation of Repolarization Process Based on KCNQI and KCNEl Expression Experiment T. Yamaguchi, K. Kamiya, T. Arafune, K. Ouchi, E. Watanabe, H. Honjo, I. Kodama, N. Shibata and I. Sakuma......Page 864
1. Introduction......Page 865
2. Methods......Page 866
3.2. Effect of Distance between Lines of Discontinuity on RPA Induction......Page 867
4. Discussion......Page 868
References......Page 869
18 Ablation......Page 870
New Ablation Technologies for VT A. d'Avila......Page 872
Conclusion......Page 873
2.1. Patient I......Page 874
2.2. Patient 2......Page 879
3.1. Main Findings......Page 881
3.3. Induction Method of the PVT and the Pharmacological Effects......Page 882
References......Page 883
Endocardial Electroahatomical Substrate and Catheter Ablation in Patients with Nonischemic Cardiomyopathy and Monomorphic Ventricular TachycGdia K. Satomi......Page 885
Author Index......Page 888