Advanced Bioimaging Technologies in Assessment of the Quality of Bone and Scaffold Materials: Techniques and Applications

Front Matter....Pages I-XV
Front Matter....Pages 1-1
Perspectives on Advances in Bone Imaging for Osteoporosis....Pages 5-26
Bone Structure and Biomechanical Analyses Using Imaging and Simulation Technology....Pages 27-50
Imaging Technologies for Orthopaedic Visualization and Simulation....Pages 51-64
In-Vivo Bone Mineral Density and Structures in Humans: From Isotom Over Densiscan to Xtreme-CT....Pages 65-78
Calibration of Micro-CT Data for Quantifying Bone Mineral and Biomaterial Density and Microarchitecture....Pages 79-84
Repositioning of the Region of Interest in the Radius of the Growing Child in Follow-up Measurements by pQCT....Pages 85-102
Non-invasive Bone Quality Assessment Using Quantitative Ultrasound Imaging and Acoustic Parameters....Pages 103-131
Cortical Bone Mineral Status Evaluated by pQCT, Quantitative Backscattered Electron Imaging and Polarized Light Microscopy....Pages 135-161
High-Fidelity Histologic Three-Dimensional Analysis of Bone and Cartilage....Pages 163-171
Application of Laser Scanning Confocal Microscopy in Musculoskeletal Research....Pages 173-189
Fiber-optic Nano-biosensors and Near-Field Scanning Optical Microscopy for Biological Imaging....Pages 191-203
Changes of Biological Function of Bone Cells and Effect of Anti-osteoporosis Agents on Bone Cells....Pages 205-222
Bone Histomorphometry in Various Metabolic Bone Diseases Studied by Bone Biopsy in China....Pages 223-225
Cell Traction Force Microscopy....Pages 227-235
Contrast-Enhanced Micro-CT Imaging of Soft Tissues....Pages 239-256
Materials Selection and Scaffold Fabrication for Tissue Engineering in Orthopaedics....Pages 259-288
Quantification of Porosity, Connectivity and Material Density of Calcium Phosphate Ceramic Implants Using Micro-Computed Tomography....Pages 289-305
Bone Densitometries in Assessing Bone Mineral and Structural Profiles in Patients with Adolescent Idiopathic Scoliosis....Pages 307-322
Application of Nano-CT and High-Resolution Micro-CT to Study Bone Quality and Ultrastructure, Scaffold Biomaterials and Vascular Networks....Pages 323-331
Bio-imaging Technologies in Studying Bone-Biomaterial Interface: Applications in Experimental Spinal Fusion Model....Pages 333-351
Front Matter....Pages 1-1
Assessment of Bone, Cartilage, Tendon and Bone Cells by Confocal Laser Scanning Microscopy....Pages 353-367
Front Matter....Pages 369-369
TEM Study of Bone and Scaffold Materials....Pages 373-392
Material and Structural Basis of Bone Fragility: A Rational Approach to Therapy....Pages 393-398
Application of Micro-CT and MRI in Clinical and Preclinical Studies of Osteoporosis and Related Disorders....Pages 399-415
CT-Based Microstructure Analysis for Assessment of Bone Fragility....Pages 417-429
Discrimination of Contributing Factors to Bone Fragility Using vQCT In Vivo....Pages 431-449
Osteoporosis Research with the vivaCT40....Pages 451-462
Mechanical Properties of Vertebral Trabeculae with Ageing Evaluated with Micro-CT....Pages 463-473
MRI Evaluation of Osteoporosis....Pages 475-484
Multiple Bio-imaging Modalities in Evaluation of Epimedium-Derived Phytoestrogenic Fraction for Prevention of Postmenopausal Osteoporosis....Pages 485-504
Areal and Volumetric Bone Densitometry in Evaluation of Tai Chi Chuan Exercise for Prevention of Postmenopausal Osteoporosis....Pages 505-515
Enhancement of Osteoporotic Bone Using Injectable Hydroxyapatite in OVX Goats Evaluated by Multi-imaging Modalities....Pages 517-527
Quality of Healing Compared Between Osteoporotic Fracture and Normal Traumatic Fracture....Pages 531-541
Monitoring Fracture Healing Using Digital Radiographies....Pages 543-552
Fracture Callus Under Anti-resorptive Agent Treatment Evaluated by pQCT....Pages 553-566
Volumetric Measurement of Osteonecrotic Femoral Head Using Computerized MRI and Prediction For Its Mechanical Properties....Pages 569-577
Biomedical Engineering in Surgical Repair of Osteonecrosis: the Role of Imaging Technology....Pages 579-591
Contrast-Enhanced MRI and Micro-CT Adopted for Evaluation of a Lipid-Lowering and Anticoagulant Herbal Epimedium-Derived Phytoestrogenic Extract for Prevention of Steroid-Associated Osteonecrosis....Pages 593-611
Nanomechanics of Bone and Bioactive Bone-Cement Interfaces....Pages 613-625
Subchondral Bone Microarchitecture Changes in Animal Models of Arthritis....Pages 629-640
Front Matter....Pages 369-369
Microarchitectural Adaptations of Primary Osteoarthrotic Subchondral Bone....Pages 641-655
Ultrasonic Characterization of Dynamic Depth-Dependent Biomechanical Properties of Articular Cartilage....Pages 657-671
Mechanical Property of Trabecular Bone of the Femoral Heads from Osteoarthritis and Osteoporosis Patients....Pages 673-690
Back Matter....Pages 691-700