A New Era of Catecholamines in the Laboratory and Clinic

Content: 
Copyright
Page iv

Preface
Pages xiii-xv
Lee E. Eiden

Contributors
Pages xvii-xxi

Chapter One - Intracellular Stability of Tyrosine Hydroxylase: Phosphorylation and Proteasomal Digestion of the Enzyme
Pages 3-11
Akira Nakashima, Yoko S. Kaneko, Yu Kodani, Keiji Mori, Hiroshi Nagasaki, Toshiharu Nagatsu, Akira Ota

Chapter Two - Tyrosine Hydroxylase: Regulation by Feedback Inhibition and Phosphorylation
Pages 13-21
Phillip W. Dickson, Gabrielle D. Briggs

Chapter Three - GTP Cyclohydrolase Regulation: Implications for Brain Development and Function
Pages 23-35
Hiroshi Ichinose, Daigo Homma, Chiho Sumi-Ichinose, Takahide Nomura, Kazunao Kondo

Chapter Four - Brain Neurons Partly Expressing Dopaminergic Phenotype: Location, Development, Functional Significance, and Regulation
Pages 37-91
Michael V. Ugrumov

Chapter Five - Granins and Catecholamines: Functional Interaction in Chromaffin Cells and Adipose Tissue
Pages 93-113
Ricardo Borges, Natalia Dominguez, Corey B. Smith, Gautam K. Bandyopadhyay, Daniel T. O\'Connor, Sushil K. Mahata, Alessandro Bartolomucci

Chapter Six - Interactions of Neuropeptide Y, Catecholamines, and Angiotensin at the Vascular Neuroeffector Junction
Pages 115-139
Thomas C. Westfall, Heather Macarthur, Mirnela Byku, Chun-Lian Yang, Jessica Murray

Chapter Seven - Neural Circuit Mechanism for Learning Dependent on Dopamine Transmission: Roles of Striatal Direct and Indirect Pathways in Sensory Discrimination
Pages 143-153
Kazuto Kobayashi, Ryoji Fukabori, Kayo Nishizawa

Chapter Eight - Selective Ablation of Dopamine β-Hydroxylase Neurons in the Brain by Immunotoxin-Mediated Neuronal Targeting: New Insights into Brain Catecholaminergic Circuitry and Catecholamine-Related Diseases
Pages 155-166
Keiichi Itoi, Shinji Ohara, Kazuto Kobayashi

Chapter Nine - Catecholamine/Serotonin Interactions: Systems Thinking for Brain Function and Disease
Pages 167-197
Julie G. Hensler, Francesc Artigas, Analía Bortolozzi, Lynette C. Daws, Philippe De Deurwaerdère, Léa Milan, Sylvia Navailles, Wouter Koek

Chapter Ten - The Enduring Centrality of Dopamine in the Pathophysiology of Schizophrenia: In Vivo Evidence from the Prodrome to the First Psychotic Episode
Pages 199-220
Ilaria Bonoldi, O.D. Howes

Chapter Eleven - Catecholamine Metabolites Affected by the Copper-Dependent Enzyme Dopamine-Beta-Hydroxylase Provide Sensitive Biomarkers for Early Diagnosis of Menkes Disease and Viral-Mediated ATP7A Gene Therapy
Pages 223-233
Stephen G. Kaler, Courtney S. Holmes

Chapter Twelve - Biomarkers, Mechanisms, and Potential Prevention of Catecholamine Neuron Loss in Parkinson Disease
Pages 235-272
David S. Goldstein

Chapter Thirteen - AADC Deficiency: Occurring in Humans, Modeled in Rodents
Pages 273-284
Wuh-Liang Hwu, Ni-Chung Lee, Yin-Hsiu Chien, Shin-ichi Muramatsu, Hiroshi Ichinose

Chapter Fourteen - Role of Hypoxia and HIF2α in Development of the Sympathoadrenal Cell Lineage and Chromaffin Cell Tumors with Distinct Catecholamine Phenotypic Features
Pages 285-317
Susan Richter, Nan Qin, Karel Pacak, Graeme Eisenhofer

Chapter Fifteen - Localization and Expression of VMAT2 Aross Mammalian Species: A Translational Guide for Its Visualization and Targeting in Health and Disease
Pages 319-334
Martin K.-H. Schafer, Eberhard Weihe, Lee E. Eiden

Chapter Sixteen - Catecholamine Receptors: Prototypes for GPCR-Based Drug Discovery
Pages 335-356
Andrew C. Emery

Chapter Seventeen - Stress-Triggered Changes in Peripheral Catecholaminergic Systems
Pages 359-397
Richard Kvetnansky, Xiaojiong Lu, Michael G. Ziegler

Chapter Eighteen - Neuropeptide–Catecholamine Interactions in Stress
Pages 399-404
Lee E. Eiden

Chapter Nineteen - Neuropeptide Regulation of the Locus Coeruleus and Opiate-Induced Plasticity of Stress Responses
Pages 405-420
Elisabeth J. Van Bockstaele, Rita J. Valentino

Chapter Twenty - Identifying Links in the Chain: The Dynamic Coupling of Catecholamines, Peptide Synthesis, and Peptide Release in Hypothalamic Neuroendocrine Neurons
Pages 421-444
Alan G. Watts, Arshad M. Khan

Chapter Twenty-One - Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP): A Master Regulator in Central and Peripheral Stress Responses
Pages 445-457
Tomris Mustafa

Index
Pages 459-477