A Molecular and Cellular View of Protein Kinase CK2

Front Matter....Pages i-2
CK2, a protein kinase of the next millennium....Pages 3-12
A multifunctional network of basic residues confers unique properties to protein kinase CK2....Pages 13-19
Intermolecular contact sites in protein kinase CK2....Pages 21-28
Binding of polylysine to protein kinase CK2, measured by Surface Plasmon Resonance....Pages 29-33
Functional analysis of CK2β-derived synthetic fragments....Pages 35-42
Dissecting subdomains involved in multiple functions of the CK2β subunit....Pages 43-50
Interactions of protein kinase CK2β subunit within the holoenzyme and with other proteins....Pages 51-58
CK2α loci in the human genome: Structure and transcriptional activity....Pages 59-64
Murine protein kinase CK2: Gene and oncogene....Pages 65-74
Interactions of protein kinase CK2 subunits....Pages 75-83
Mutations in the C-terminal domain of topoisomerase II affect meiotic function and interaction with the casein kinase 2 β subunit....Pages 85-95
Association of protein kinase CK2 with eukaryotic translation initiation factor eIF-2 and with grp94/endoplasmin....Pages 97-104
Searching interaction partners of protein kinase CK2β subunit by two-hybrid screening....Pages 105-109
Protein kinase CK2 interacts with a multi-protein binding domain of p53....Pages 111-120
BTF3 is a potential new substrate of protein kinase CK2....Pages 121-128
Protein kinase CK2α may induce gene expression but unlikely acts directly as a DNA-binding transcription-activating factor....Pages 129-134
Role of protein kinase CK2 in phosphorylation of nucleosomal proteins in relation to transcriptional activity....Pages 135-142
A review of progress towards elucidating the role of protein kinase CK2 in polymerase III transcription: Regulation of the TATA binding protein....Pages 143-148
The binding of the α subunit of protein kinase CK2 and RAP74 subunit of TFIIF to protein-coding genes in living cells is DRB sensitive....Pages 149-159
Transcriptional regulation of the S. cerevisiae ENA1 gene by casein kinase II....Pages 161-167
A role for casein kinase II phosphorylation in the regulation of IRF-1 transcriptional activity....Pages 169-180
A structural model for elongation factor 1 (EF-1) and phosphorylation by protein kinase CKII....Pages 181-186
Protein kinase CK2-dependent regulation of p53 function: Evidence that the phosphorylation status of the serine 386 (CK2) site of p53 is constitutive and stable....Pages 187-199
Distribution of CK2, its substrate MAP1B and phosphatases in neuronal cells....Pages 201-205
CK2α — protein phosphatase 2A molecular complex: Possible interaction with the MAP kinase pathway....Pages 207-212
Expression and regulation of protein kinase CK2 during the cell cycle....Pages 213-222
Identification of proteins that associate with protein kinase CK2....Pages 223-228
Multiple forms of protein kinase CK2 present in leukemic cells: In vitro study of its origin by proteolysis....Pages 229-234
Back Matter....Pages 235-239