A Life Decoded: My Genome: My Life

Cover......Page 1
Copyright page......Page 8
Contents......Page 11
A happy seven-year-old enjoying life.......Page 15
Mills High School graduation photo, 1964.......Page 16
Sea-snake skin pinned to a board with hypodermic needles while drying in the hot sun outside of a bunker.......Page 17
Treating patients at an orphanage outside of Da Nang in 1968.......Page 18
Single-handed sailing on PAIX out the channel from Mission Bay into the Pacific Ocean.......Page 19
A winter break at Falling Leaf Lake, near Lake Tahoe, with Christopher, Barbara, and dear friends and College of San Mateo mentor Bruce Cameron and his wife, Pat Cameron.......Page 20
As a single parent celebrating Christopher's third birthday in an old row house near the Buffalo Medical School, 1980.......Page 21
My father after a good day of golf, shortly before he died in his sleep on June 10, 1982, from sudden cardiac death.......Page 22
In my NIH lab, trying to boost the morale of my team after The Washington Post reported that Jim Watson had declared at a Senate hearing that monkeys could do my EST method of gene discovery. Claire bravely wore the monkey suit to mock Watson.......Page 23
Receiving the New York Yacht Club trophy for winning the contemporary division of the transatlantic race from Commodore Bob James in Falmouth, England, in 1997.......Page 24
Meeting with Ari Patrinos and Francis Collins at the White House prior to the announcement of the sequencing of the human genome, and seeing the Time magazine cover for the first time.......Page 25
Taking questions from the White House press corps with Ari Patrinos, Francis Collins, and the White House science adviser Neil Lane.......Page 26
Gene Myers, Mark Adams, and me waiting for the onslaught of questions from a packed ballroom at the Washington Hilton genome press conference.......Page 27
The issue of Science featuring my team's description of the human genome.......Page 28
The ninety-five-foot Sorcerer II in the Galapagos Islands at the Master and Commander movie site.......Page 29
Me with fiancée Heather E. Kowalski.......Page 30
Introduction......Page 31
1  Writing My Code......Page 35
My DNA, My Life......Page 37
The Y and the Wherefore......Page 39
Blame It on My Genes......Page 45
My Y Chromosome and Sex......Page 48
2  University of Death......Page 57
Endurance......Page 58
Night Genes......Page 60
Genes and Addictions......Page 61
3  Adrenaline Junkie......Page 79
My Genome and My Brother......Page 84
4  Starting Over in Buffalo......Page 105
My Asthma and My Genes......Page 109
My Father's Genetic Bequest......Page 115
Ouch!......Page 117
5  Scientific Heaven, Bureaucratic Hell......Page 119
6  Big Biology......Page 155
When Caffeine Kills......Page 162
Watson Got It Right. I Am a Primate.......Page 166
The Fat Gene......Page 170
A Gene Fit for Wally......Page 180
7  TIGRCub......Page 189
My Risk Genes......Page 191
8  Gene Wars......Page 201
Stress, Impulsivity, and Thrill Seeking......Page 209
9  Shotgun Sequencing......Page 219
10  Institutional Divorce......Page 246
My Fickle Heart......Page 247
Skipping a Heartbeat......Page 249
11  Sequencing the Human......Page 257
My Waistline and Diabetes......Page 258
12  Mad Magazine and Destructive Businessmen......Page 284
Genes Are Not the Whole Story......Page 288
13  Flying Forward......Page 297
14  The First Human Genome......Page 311
The Eyes Have It......Page 314
15  The White House, June 26, 2000......Page 340
16  Publish and Be Damned......Page 350
Depression......Page 359
Beyond the Genome......Page 362
17  Blue Planet and New Life......Page 363
Blinding Discovery......Page 369
Cancer and My Genome......Page 370
Sequencing and Cancer......Page 372
Long Life?......Page 382
Acknowledgments......Page 389
3  Adrenaline Junkie......Page 391
6  Big Biology......Page 392
8  Gene Wars......Page 393
9  Shotgun Sequencing......Page 394
11  Sequencing the Human......Page 396
13  Flying Forward......Page 397
14  The First Human Genome......Page 398
16  Publish and Be Damned......Page 400
17  Blue Planet and New Life......Page 402
B......Page 405
C......Page 406
D......Page 408
F......Page 409
H......Page 410
I......Page 411
L......Page 412
N......Page 413
P......Page 414
R......Page 415
S......Page 416
T......Page 417
V......Page 418
W......Page 419
Z......Page 420